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Research Progress on the Nonstructural Proteins of Porcine Reproductive and Respiratory Syndrome Virus
Authors:LIU Ya-li  DING Yao-zhong  ZHANG Jie
Institution:State Key Laboratory on Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China
Abstract:Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease that spreads all over the world.It is caused by porcine reproductive and respiratory syndrome virus (PRRSV).Once infected with PRRSV,NSPs (nonstructural proteins) were expressed firstly.At least 14 kinds of NSPs,including NSP1α,NSP1β,NSP2,NSP3,NSP4,NSP5,NSP6,NSP7a,NSP7b,NSP8,NSP9,NSP10,NSP11 and NSP12,were produced during PRRSV life,which plays an important role in virus proliferation,virus virulence,immunological characteristics and so on.In this paper,we make a brief overview in terms of the research progress on NSPs to make a basis for the prevention of PRRS.
Keywords:porcine reproductive and respiratory syndrome virus  nonstructural proteins  immunological characteristics  
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