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| 水貂阿留申病病毒分子生物学研究进展 | |
| 引用本文： | 李艳伍,张瑞,姜平,贾赟.水貂阿留申病病毒分子生物学研究进展[J].动物医学进展,2009,30(9):100-104. |
| 作者姓名： | 李艳伍 张瑞 姜平 贾赟 |
| 作者单位： | 1. 南京农业大学动物医学院,江苏南京,210095;辽宁出入境检验检疫局,辽宁大连,116001 2. 河南农业大学牧医工程学院,河南郑州,450002 3. 南京农业大学动物医学院,江苏南京,210095 4. 辽宁出入境检验检疫局,辽宁大连,116001 |
| 摘 要： | 水貂阿留申病病毒是一种在水貂中广泛存在的重要病原体.该病毒属阿留申病毒属,主要编码4种蛋白(结构蛋白VP1、VP2和非结构蛋白NS1、NS2).VP1蛋白在协助病毒产生感染性方面起着重要作用;VP2蛋白是该病毒的主要免疫原性抗原,能体外中和病毒;NS1和NS2对病毒在宿主细胞中的复制起重要的调节作用.该病毒的分子生物学诊断技术主要有核酸杂交技术、PCR和基因芯片检测技术. |
| 关 键 词： | 水貂阿留申病病毒 结构蛋白 非结构蛋白 分子生物学诊断技术 |
Advance in Molecular Biology of Aleutian mink disease virus |
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| LI Yan-wu,ZHANG Rui,JIANG Ping,JIA Yun.Advance in Molecular Biology of Aleutian mink disease virus[J].Progress In Veterinary Medicine,2009,30(9):100-104. | |
| Authors: | LI Yan-wu ZHANG Rui JIANG Ping JIA Yun |
| Institution: | LI Yan-wu1,2,ZHANG Rui3,JIANG Ping1,JIA Yun2(1.College of Veterinary Medicine,Nanjing Agricultural University,Nanjing,Jiangsu 210095,China,2.Liaoning Entry-Exit Inspection and Quarantine Bureau,Dalian,Liaoning,116001,3.Engineering College of Animal Husbandry and Veterinary Science,Henan Agricultural University,Zhengzhou,Henan 450002,China) |
| Abstract: | Aleutian mink disease virus(ADV) is a widespread existence of important pathogens in mink.ADV is a member of the genus Amdovirus,which encodes four proteins(structural proteins VP1,VP2 and non-structural proteins NS1,NS2).VP1 protein plays an important role in helping to produce infectious virus,VP2 protein is the major virus antigen of immunogenicity,which could neutralize virus in vitro;NS1 and NS2 play an important regulation role in virus replication in host cells.The molecular biological diagnostic tec... |
| Keywords: | Aleutian mink disease virus structural protein non-structural proteins molecular biological diagnostic techniques |
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