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猫杯状病毒基因组结构与结构蛋白功能研究进展
引用本文:王延树,向华,程淑琴.猫杯状病毒基因组结构与结构蛋白功能研究进展[J].中国兽药杂志,2007,41(6):29-33.
作者姓名:王延树  向华  程淑琴
作者单位:1. 吉林大学畜牧兽医学院,吉林长春,130062;广东省农科院兽医研究所,广东广州,510640
2. 广东省农科院兽医研究所,广东广州,510640
3. 河北旅游职业学院,河北承德,067000
摘    要:猫杯状病毒是一种引起猫的急性口腔溃疡、上呼吸道传染病和慢性胃肠炎等病的重要病原。近年来,随着对其研究的不断深入,在病毒分子生物学方面取得了很大的进展。本文主要从基因组结构、编码的结构蛋白功能、基因疫苗等方面系统阐述了猫杯状病毒的研究进展,同时提出了存在的问题和展望。为进一步研制猫杯状病毒基因工程疫苗及诊断试剂提供理论基础,以期能更有效地防治此病。

关 键 词:猫杯状病毒  衣壳蛋白  抗原表位
文章编号:1002-1280(2007)06-0029-05
修稿时间:2006-12-26

Research Progress in the Genome Structure and Structural Protein Function of Feline Calicivirus
WANG Yan-shu,XIANG Hua,CHENG Shu-qin.Research Progress in the Genome Structure and Structural Protein Function of Feline Calicivirus[J].Chinese Journal of Veterinary Drug,2007,41(6):29-33.
Authors:WANG Yan-shu  XIANG Hua  CHENG Shu-qin
Institution:1. College of Veterinary Medicine, Jilin University , Changchun, Jilin, 130062 ; 2. Institute of Veterinary Medicine Gnangdong Academy of Agricultural Scienses , Guangzhou , Guang dong , 510640 ; 3. Hebei Tourism Vocational College, Chengde ,Hebei , 067000; China
Abstract:Feline calicivirus(FCV) causing upper respiratory tract disease and acute mouth ulceration,was occasionally associated with chronic stomostitis and acute arthritis in cats.The great progress was made in molecular biology of FCV after studying thoroughly these years.This article reviewed the advances in structure of genome,function of coding proteins and gene vaccine of FCV.Future developments and recent problems were mentioned.It will supply important theoretical foundation for researching immunity and diagnostic products of genetic engineering and detecting and preventing FCV in order to control the disease more effectively.
Keywords:feline calicivirus  capsid protein  epitope
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