| 响应面法优化茅苍术多糖的提取工艺 |
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| 引用本文： | 徐秀泉,于荣敏,刘柯,罗明.响应面法优化茅苍术多糖的提取工艺[J].安徽农业科学,2011,39(20):12082-12085. |
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| 作者姓名： | 徐秀泉 于荣敏 刘柯 罗明 |
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| 作者单位： | 1. 江苏大学药学院,江苏,镇江,212013
2. 暨南大学药学院,广东,广州,510632 |
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| 基金项目： | 江苏大学高级人才专项补助，江苏大学大学生科研立项项目 |
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| 摘 要： | 目的]利用响应面分析法优化茅苍术多糖的提取工艺。方法]根据中心组合设计原理,以提取温度、提取时间、料液比三个因素为自变量,多糖的提取得率为响应值,设计了3因素3水平响应面分析试验,来确定茅苍术多糖提取的最佳工艺条件。结果]茅苍术多糖提取的最佳工艺条件为：提取温度87℃,料液比1∶22,提取时间3.1 h。在此最佳条件下,茅苍术多糖的提取率为2.12%。结论]该研究对大规模提取茅苍术多糖有一定理论指导价值。
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| 关 键 词： | 茅苍术（RHIZOMA AREACTYLODIS LANCEAE） 多糖 提取 响应面 |
Optimization of Extraction Process of Polysaccharides from,RHIZOMA AREACTYLODIS LANCEAE by Response Surface Methodology |
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| Institution: | XU Xiu-quan et al (College of Pharmacy,Jiangsu University,Zhenjiang,Jiangsu 212013) |
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| Abstract: | Objective] To optimize the extraction process of polysaccharides from RHIZOMA AREACTYLODIS LANCEAE by response surface methodology.Method] Using extraction temperature,solid-liquid ratio and extraction time as independent variables and extraction rate of polysaccharides as response value,response surface methodology with three-factors and three-levels was carried out for optimizing the extraction process of polysaccharides from RHIZOMA AREACTYLODIS LANCEAE on the basis of central composite design principles.Result] The optimum extraction conditions of polysaccharides were as follows: extraction temperature of 87 ℃,solid-liquid ratio of 1∶22 and extraction time of 3.1 h.Under this condition,the extraction rate of polysaccharides was 2.12%.Conclusion] The study could provide a certain theoretical direction for extracting polysaccharides from RHIZOMA AREACTYLODIS LANCEAE on a large scale. |
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| Keywords: | RHIZOMA AREACTYLODIS LANCEAE Polysaccharides Extraction Response surface methodology |
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