2. As the environment can be viewed as a composite of interacting stressors, the bird's success in coping with its environment depends on the severity of the stressors and the physiological ability to respond properly and thus maintain homeostasis.

3. The neural, endocrine and more recently immune systems are considered to be integrators of the stress response. Although stress responses may be necessary for survival in wild bird populations, they are often detrimental to efficient growth, skeletal integrity and disease resistance in domesticated fowl.

4. Stress responses are modified by the genetic components.