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镉污染对鲢抗氧化防御系统影响研究
引用本文:吕景才,宋晓阳,王凡,赵元凤,孙静,潘德建,侯美艳,刘恒明.镉污染对鲢抗氧化防御系统影响研究[J].西南农业大学学报,2002,24(6):491-493,505.
作者姓名:吕景才  宋晓阳  王凡  赵元凤  孙静  潘德建  侯美艳  刘恒明
作者单位:大连大产学院养殖系,辽宁大连116023
基金项目:辽宁省科委基金项目资助 (0 0 1 0 55),辽宁省教育厅项目资助 (2 0 1 0 1 2 33)
摘    要:采用毒性实验方法,研究了不同浓度的镉(Cd^2 )对鲢几种组织内抗氧化防御系统酶-超氧化物歧化酶(SOD)活性的影响。结果表明,在实验剂量范围内,Cd^2 对鲢几种组织内SOD活性均有不同程度诱导,其剂量-效应曲线均为抛物线,即低浓度Cd^2 对SOD超诱导作用,高浓度则起抑制作用。不同组织内SOD对Cd^2 的敏感性不同,按敏感性大小顺序排列为:血清>肝脏=鳃>肌肉;按Cd^2 对不同组织SOD活性最大诱导倍数高低次序排列为:血清>肝脏>鳃>肌肉;表明,灵敏指示Cd^2 对鲢胁迫程度的优选组织是血清,其次是肝脏。

关 键 词:镉污染    抗氧化防御系统  影响  超氧化物歧化酶  淡水鱼类
文章编号:1000-2642(2002)06-0491-03

THE EFFECTS OF CADMIUM POLLUTION ON THE ANTIOXIDANT DEFENSE SYSTEM OF ARISTCHTHUS NOBILIS
Abstract:A toxic experiment was made to study the effect of different concentration of cadmium (Cd 2+ ) on the activity of the antioxidant defense system, i.e. superoxide dismutase (SOD) in different tissues, of Aristchthys nobilis. The results showed that within the dosages adopted in the experiment, Cd 2+ induced, in different degrees, SOD activity in the tissues of Aristchthys nobilis . The dosage-effect curves were all parabolic, suggesting that low concentration of Cd 2+ induced SOD while high Cd 2+ concentration inhibited it. The sensitivity of SOD to Cd 2+ differed with tissue, being serum > liver = gill >muscle, and the maximal induction multiple sequence of Cd 2+ on SOD appeared to be serum > liver > gill > muscle. Such results showed that the optimum seeking tissue for the indication of Cd 2+ coercion on Aristchthys nobilis should be serum, followed by liver.
Keywords:Aristchthys nobilis  superoxide dismutase (SOD)  cadmium (Cd    2+  )
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