| 雏鸡接种新城疫霍乱毒素B亚单位佐剂苗抗体效价的检测 |
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| 引用本文： | 孙宏君,刘冰,孙斌,吴凌.雏鸡接种新城疫霍乱毒素B亚单位佐剂苗抗体效价的检测[J].吉林畜牧兽医,2004(7):24-26. |
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| 作者姓名： | 孙宏君 刘冰 孙斌 吴凌 |
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| 作者单位： | 黑龙江哈尔滨市畜牧兽医技术服务中心,黑龙江,哈尔滨,150016;黑龙江八一农垦大学动科院,黑龙江,密山,158308 |
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| 摘 要： | 选取1日龄商品蛋用雏母鸡100只，随机分为对照组(接种ND疫苗)和试验组(接种NDV4．CTB苗)，每组50只，免疫后1周、2周采取两组的血清和泪液，检测ND的抗体效价(HI抗体滴度)。结果显示：接种NDV4-CTB的雏鸡，血清ND抗体效价持续升高，并且泪液的ND抗体效价升高的快而持续。表明接种NDV4-CTB的雏鸡体液免疫和局部(哈氏腺)免疫都得到增强，有利于抵抗ND病毒的感染。CT-B对雏鸡具有抗免疫抑制的作用。
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| 关 键 词： | 霍乱毒素B亚单位 疫苗 新城疫 雏鸡 |
Detection to the ND's antibody valence chickens inoculated by ND-CTB subunit adjuvant vaccine |
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| SUN Hong-jun,LIU Bing,Sun Bin,Wu Ling.Detection to the ND's antibody valence chickens inoculated by ND-CTB subunit adjuvant vaccine[J].Jilin Animal Science and Veterinary Medicine,2004(7):24-26. |
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| Authors: | SUN Hong-jun LIU Bing Sun Bin Wu Ling |
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| Abstract: | 100 1-day commercial female chickens were randomly divided into two groups that contain respectively 50 chickens. One group that inoculated by NDV4-CTB is test group, another that inoculated by NDV4 is control group. After 1,2 week of vaccination, the ND's antibody titer of two groups of chickens in serum and tear juice are detected. Result shown that ND's antibody valence of test group rise persistently in serum. And elevates rapidly and long in tear juice. These indicate that humoral and local immunity of chicken inoculated by NDV4-CTB subunit vaccine is enhanced. It is favor to resist ND infection.CT-B has autoimmunity abatement effects to chickens. |
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| Keywords: | cholera toxin B subunit vaccine Newcastle disease |
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