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Effect of cobra venom factor on experimental infection of mice against Clostridium chauvoei.
Authors:Y Tamura  M Kijima  S Suzuki  T Takahashi  M Nakamura
Institution:National Veterinary Assay Laboratory, Tokyo, Japan.
Abstract:The effect of cobra venom factor (CoVF) treatment was examined to clarify the mechanism of resistance of mice to Clostridium chauvoei infection. In CoVF-treated mice inoculated with spores of C. chauvoei, no death occurred and the organisms in the infected muscle progressively decreased, similar to that of non-treated control mice. These results indicated that C3 did not play a significant role in the resistance of mice against C. chauvoei infection.
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