Estimation of residues of the molluscicide,niclosamide, in bananas by gas—liquid chromatography of the heptafluorobutyryl derivative of the substituted aniline moiety |
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| Authors: | John S Johnson Geoffrey B Pickering |
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| Abstract: | A sensitive method for the detection and estimation of residues of the molluscicide, niclosamide, in bananas is described. The procedure involves extraction of the molluscicide, purification of the extract by solvent partition and column chromatography, formation of the heptafluorobutyryl derivative of 2-chloro-4-nitroaniline in 99% yield and determination of the derivative by gas—liquid chromatography with electron-capture detection. Recoveries from fortified bananas were 89 and 79% at levels of 0.02 and 0.2 mg kg?1, respectively. The sensitivity of the method was such that 0.6 pg of the pure derivative could be detected, based on twice the background noise level on the chromatograph. |
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