| 弓形虫P30基因及其功能 |
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| 引用本文： | 徐大刚.弓形虫P30基因及其功能[J].中国兽医寄生虫病,2002(3). |
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| 作者姓名： | 徐大刚 |
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| 作者单位： | 上海第二医科大学病原生物学教研室 上海200030 |
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| 摘 要： | 弓形虫 P30基因所编码的蛋白为弓形虫主要表面抗原 SAG1 ,其约占速殖子总蛋白量的 5 %,SAG1对虫体侵入宿主细胞及其毒力具重要性 ,并有高度免疫原性和免疫保护性 ,被用于弓形虫疫苗的研制和弓形虫感染的分子诊断
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| 关 键 词： | SAG1 弓形虫的毒力 疫苗 分子诊断 |
THE P30 GENE OF TOXOPLASMA GONDII AND ITS FUNCTION |
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| XU Da,gang.THE P30 GENE OF TOXOPLASMA GONDII AND ITS FUNCTION[J].Chinese Journal of Veterinary Parasitology,2002(3). |
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| Authors: | XU Da gang |
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| Abstract: | The P30 gene encodes the major surface antigen 1(SAG1) of Toxoplasma gondii . SAG1 marks up at about 5% of the total protein of T. gondii tachyzoites. It has been indicated that this protein has a role in host cell adhesion, invasion and toxicity. Because the host immune responses can be induced with the protein that are protective to the parasite infection, the gene is studied on vaccine development and toxoplasmosis molecular diagnosis. |
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| Keywords: | Toxoplasma gondii P30 gene toxicity vaccine diagnosis |
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