Quantitative structure-activity relationships of herbicidal N′-substituted phenyl-N-methoxy-N-methylureas |
| |
| Authors: | Ichiki Takemoto Ryo Yoshida Seizo Sumida Katsuzo Kamoshita |
| |
| Institution: | Pesticide Research Laboratory, Takarazuka Research Center, Sumitomo Chemical Company, Ltd., 4-2-1 Takatsukasa, Takarazuka, Hyogo 665, Japan |
| |
| Abstract: | Relationships between three types of herbicidal activity of N′-substituted phenyl-N-methoxy-N-methylureas and substitution at the benzene ring were analyzed by the Hansch-Fujita method. First, the Hill inhibitory activity was correlated with electronic (σ) as well as hydrophobic (π) substituent constants. The existence of an optimum value of hydrophobicity for substituents was suggested to reach the target site of action. Second, bliaching activity observed for the 3-substituted but not for 4-substituted compounds was correlated with π, σ, and steric substituent constant, Es. Third, the postemergent herbicidal activity was shown to correlate linearly with the Hill inhibitory activity, pI50, and hydrophobic parameter, π. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
