Insulin-like growth factors and recurrent hypoglycemia associated with renal cell carcinoma in a horse |
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| Authors: | Swain J M Pirie R S Hudson N P H Else R W Evans H McGorum B C |
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| Institution: | Division of Veterinary Clinical Studies, Royal School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, EH25 9RG, UK. jennyswain@hotmail.com |
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| Abstract: | The case was examined at the Easter Bush Veterinary Hospital, The University of Edinburgh. A 520 kg, 6-year-old Thoroughbred gelding was referred for evaluation of acute onset profound depression, head pressing, and lack of response to external stimuli. The horse had a history of moderate weight loss over several months despite adequate nutrition and a good appetite. Previous episodes of weakness had been observed following administration of anthelmintics, namely, alternate doses of pyrantel and ivermectin, administered every 8 weeks. In an attempt to eliminate a possible parasitic cause of weight loss, over the 7 days prior to presentation, the referring veterinary surgeon treated the horse with a 5-day course of fenbendazolea (7.5 mg/kg PO q24h) and moxidectinb (0.4 mg/kg PO), 2 days later. A 5-day course of prednisolonec (1 mg/kg PO q24h) was initiated on the same day as the fenbendazole. This dose was then tapered to 0.5 mg/kg PO q24h, and was still being administered at the time of presentation. |
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