|
|||||
|
|
| 减毒鸡沙门菌疫苗株97A的免疫保护效力试验 | |
| 引用本文： | 刘海侠,王宝安,潘志明,黄金林,焦新安.减毒鸡沙门菌疫苗株97A的免疫保护效力试验[J].动物医学进展,2006,27(4):75-79. |
| 作者姓名： | 刘海侠 王宝安 潘志明 黄金林 焦新安 |
| 作者单位： | 1. 扬州大学兽医学院,江苏,扬州,225009 2. 扬州大学生物科学与技术学院,江苏,扬州,225009 3. 扬州大学兽医学院,江苏,扬州,225009;扬州大学生物科学与技术学院,江苏,扬州,225009 |
| 基金项目： | 中国科学院资助项目;教育部"高校青年教师奖" |
| 摘 要： | 减毒沙门菌疫苗株97A免疫鸡经鸡沙门菌强毒株Sg9攻击后,对免疫攻毒组和攻毒对照组鸡进行病理学检查和细菌分离,以进一步评价97A疫苗的免疫保护效力。结果表明,免疫攻毒组鸡肝脏、肺脏和肾脏等实质器官仅有轻到中度的炎症反应,而攻毒对照组鸡则表现出了严重的组织病理学变化,同时减毒鸡沙门菌疫苗株97A能显著地限制强毒株在鸡体内的定居和增殖,显示出了良好的免疫保护效力。 |
| 关 键 词： | 减毒鸡沙门菌 保护效力 病理学变化 细菌分离 |
| 文章编号： | 1007-5038（2006）04-0075-05 |
| 收稿时间： | 2005-11-03 |
| 修稿时间： | 2005年11月3日 |
The Protective Efficacy of Attenuated Salmonella gallinarum Strain 97A |
|
| LIU Hai-xia,WANG Bao-an,PAN Zhi-ming,HUANG Jin-lin,JIAO Xin-an.The Protective Efficacy of Attenuated Salmonella gallinarum Strain 97A[J].Progress In Veterinary Medicine,2006,27(4):75-79. | |
| Authors: | LIU Hai-xia WANG Bao-an PAN Zhi-ming HUANG Jin-lin JIAO Xin-an |
| Institution: | 1. College of Veterinary Medicine, Yangzhou University, Yangzhou , Jiangsu, 225009, China 2. College of Bioscience and Biotechnology , Yangzhou University, Yangzhou , Jiangsu , 885009, China |
| Abstract: | The chickens,which were vaccinated with vaccine strain 97A two weeks ago,were challenged with virulent S.gallinarum strain Sg9.In order to evaluate the protective efficacy of vaccine strain 97A,pathological and bacteriological examinations were performed in chickens in immunized and control groups.The results revealed that scattered little necrotic foci and/or mild to moderate inflammations were observed in liver,lung,kidney,and other parenchyma organs of the immunized-challenged chickens,while severe clinical signs and typical lesions were observed in the control group.The result of bacterial isolation indicated that strain 97A can limit the Sg9 strain in liver and spleen.The results mentioned above proved that strain 97A could be used as a vaccine candidateagainst Salmonella gallinarum. |
| Keywords: | attenuated Salmonella gallinarum protective efficacy pathological changes bacterial isolation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |