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牛病毒性腹泻病毒全球基因型与亚型流行情况
引用本文:谌婕,左之才,才冬杰,付星鑫,刘玲利,张义琳,苟丽萍,王娅,任志华,邓俊良.牛病毒性腹泻病毒全球基因型与亚型流行情况[J].浙江农业学报,2022,34(12):2622-2628.
作者姓名:谌婕  左之才  才冬杰  付星鑫  刘玲利  张义琳  苟丽萍  王娅  任志华  邓俊良
作者单位:1.四川农业大学 动物医学院,动物疫病与人类健康四川省重点实验室,四川 成都 6111342.罗平县农业农村局动物疫病预防控制中心,云南 曲靖 655800
基金项目:国家现代农业产业技术体系(肉牛牦牛);国家现代农业产业技术体系(CARS-37);国家现代农业产业技术体系四川肉牛创新团队项目(SCCXTD-2020-13)
摘    要:牛病毒性腹泻病毒(Bovine viral diarrhea virus,BVDV)在全球流行率较高的基因亚型是BVDV-1b,其次是1a和2a;基因亚型1t和1n的全球流行率较低,1v亚型是近年新流行的基因亚型。BVDV新基因亚型的逐年出现说明其在不断地发生遗传变异,致其防控愈发困难。欧洲国家流行的BVDV基因亚型种类最多,说明BVDV在欧洲具有更高的遗传多样性。在亚洲发现的BVDV毒株数量则明显多于其他洲,1b是亚洲流行率最高的基因亚型。BVDV-3型在欧洲被报道次数最多,在亚洲也被报道过。本文对世界范围内BVDV的流行情况进行综述,可以丰富BVDV分子流行病学数据,也可为BVDV防控提供一定的理论基础。

关 键 词:牛病毒性腹泻病毒  基因亚型  流行性  遗传多样性
收稿时间:2022-03-14

Global genotype and subgenotype prevalence of bovine viral diarrhea virus
CHEN Jie,ZUO Zhicai,CAI Dongjie,FU Xingxin,LIU Lingli,ZHANG Yilin,GOU Liping,WANG Ya,REN Zhihua,DENG Junliang.Global genotype and subgenotype prevalence of bovine viral diarrhea virus[J].Acta Agriculturae Zhejiangensis,2022,34(12):2622-2628.
Authors:CHEN Jie  ZUO Zhicai  CAI Dongjie  FU Xingxin  LIU Lingli  ZHANG Yilin  GOU Liping  WANG Ya  REN Zhihua  DENG Junliang
Institution:1. Sichuan Provincial Key Laboratory of Animal Diseases and Human Health, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611134, China
2. Animal Disease Prevention and Control Center of Agricultural and Rural Bureau of Luoping County, Qujing 655800, Yunnan, China
Abstract:The most frequently-reported Bovine viral diarrhea virus(BVDV) subgenotype was 1b, followed by 1a and 2a. 1t and 1n were the less reported subgenotypes, and 1v was a new popular subgenotype in recent years. Recently, the emergence of many new BVDV subgenotypes showed that continuous genetic variation made its prevention and control more and more difficult. The large number of various BVDV subgenotypes had been documented in European countries, indicating greater genetic diversity of BVDV in this continent. The number of BVDV strains found in Asia was significantly higher than those in other continents, and 1b was the most prevalent subgenotype in Asia. BVDV-3 had been reported most frequently in Europe and had also been reported in Asia. This study reviewed the worldwide prevalence of BVDV, enriched the molecular epidemiological data of BVDV, and provided a theoretical basis for the prevention and control of BVDV.
Keywords:Bovine viral diarrhea virus  subgenotype  prevalence  genetic diversity  
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