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Seminoma with cutaneous metastases in a dog
Authors:Spugnini E P  Bartolazzi A  Ruslander D
Institution:Department of Pathology and Experimental Veterinary Pathology, National Cancer Institute Regina Elena of Rome, Italy.
Abstract:A 10-year-old Great Pyrenees was presented for anorexia and weight loss. On physical examination, the dog was emaciated and showed a large ulcerated lesion on the right lower lip in addition to an enlarged right testicle. Fine-needle aspiration biopsy of the testicle and surgical biopsy of the lip lesion were performed; the histopathological report was consistent with metastatic seminoma. The diagnostic and therapeutic approach in this unusual metastatic seminoma is presented and compared to the previous literature. A multimodality therapy consisting of surgery and chemotherapy is proposed for the clinical management of metastatic seminoma in dogs.
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