Metabolic fate of [14C]photodieldrin in goldfish |
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Authors: | P Sudershan MAQ Khan |
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Institution: | Department of Biological Sciences University of Illinois at Chicago Circle, Chicago, Illinois 60680 USA |
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Abstract: | Goldfish (Carassius auratus) exposed to 20 parts per billion 14C]photodieldrin in a static system absorbed 80% of the radioactivity within 20 hr. The absorbed radioactivity was eliminated slowly with a half-life of 3 weeks. Photodieldrin and a ketone derivative were the major form of the radiocarbon eliminated in water, accounting for, respectively, 59 and 10.4% of the eliminated radioactivity. The ketone derivative was characterized by cochromatography (thin-layer and gas chromatography, gc) and gc-mass spectrometry. Approximately, 15 other polar and nonpolar metabolites were detected in the aqueous medium. The radioactivity in the fish consisted of 13 metabolites along with photodieldrin. Photodieldrin and the ketone derivative were the most abundant residues in the fish, accounting for 77 and 5.4% of the radioactivity, respectively. |
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