| H3亚型禽流感病毒分离株与变异株的生物学特性 |
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| 引用本文： | 崔尚金,于康震,唐秀英,刘明,田国彬,李建伟,刘尚高.H3亚型禽流感病毒分离株与变异株的生物学特性[J].中国预防兽医学报,2000(Z1). |
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| 作者姓名： | 崔尚金 于康震 唐秀英 刘明 田国彬 李建伟 刘尚高 |
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| 基金项目： | “973”项目资助!（G199011902， G199011905） |
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| 摘 要： | 本研究对分离到的Ｈ３Ｎ８禽流感病毒株（分离株Ａ／Ｃｈｉｃｋ／Ｊｉｌｉｎ／９８，以下简称Ｊ１株）和传代过程中发生变异的变异株（Ａ／Ｃｈｉｃｋ／Ｊｉｌｉｎ／９９，以下简称Ｊ２株）进行了生物学和病理学特性的初步研究，发现在相同的时间内，Ｊ１株病毒致死鸡胚数量明显高于Ｊ２株病毒，病毒ＨＡ的滴度也明显高于Ｊ２；Ｊ１株的ＩＰＶＩ为１．４４，而Ｊ２为０．６４；毒株的致病性试验与ＳＰＦ感染鸡的器官变化表明Ｊ１组的病理学变化较Ｊ２组明显，且主要的嗜器官为肺、肝、法氏囊、胸腺、脾等主要的免疫器官；本研究还对ＳＰＦ感染鸡的病变器官进行了病原学检测、病理组织检测和电镜观察。结果表明两者存在较明显的差异。
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| 关 键 词： | 禽流感病毒 H3N8 生物学特征 |
Biological Characterization of H3N8 Subtype Isolated and Variant Avian Influenza Viruse Strains |
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| CUI Shangjin,YU Kangzhen,TANG Xiuying,LIU Ming,TIAN Guobin,LI Jianwei,LIU Shanggao.Biological Characterization of H3N8 Subtype Isolated and Variant Avian Influenza Viruse Strains[J].Chinese Journal of Preventive Veterinary Medicine,2000(Z1). |
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| Authors: | CUI Shangjin YU Kangzhen TANG Xiuying LIU Ming TIAN Guobin LI Jianwei LIU Shanggao |
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| Abstract: | In this study, the biological characterization and pathological characterization of H3N8 isolated (A/Chick/Jilin/98, J1 ) and variant (A/Chick/Jilin/99, J2 ) avian influenza virus strains were studied, the resnlts showed there were obviously differences in them. But variant strains variance insufficiency. This will be benefit to the studies and prophylactic and treatment of avian influenza viruses. |
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| Keywords: | AIV H3N8 Biological characterization |
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