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Radiographic,MRI, and CT findings in a young dog with Becker-like muscular dystrophy |
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| Authors: | Giulia Costanzo Sergio Minei Eric Zini Margherita Gracis Giuseppe Lacava |
| Institution: | 1. AniCura Istituto Veterinario Novara, Granozzo con Monticello (NO), Novara, Italy;2. AniCura Istituto Veterinario Novara, Granozzo con Monticello (NO), Novara, Italy
Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland Department of Animal Medicine, Production and Health, University of Padova, Legnaro, Italy |
| Abstract: | An 8-month-old, male, crossbreed dog was presented for macroglossia, reduced mandibular extension, ptyalism, dysphagia, and regurgitation. Serum creatine kinase and aspartate aminotransferase activity were markedly increased. Thoracic radiographs showed an axial gastro-esophageal hiatal hernia, diaphragmatic thickening, and asymmetry. Magnetic resonance imaging of the head showed a severely enlarged tongue, symmetric increase in size of the geniohyoid and mylohyoid muscles, and diffuse masticatory hypomyotrophy. Whole-body CT ruled out other musculoskeletal abnormalities and further characterized the radiographic and MRI findings. Muscular histopathology was consistent with Becker muscular dystrophy. |
| Keywords: | Canine dystrophin gene masticatory myopathy muscular biopsy |