| 广东鸡致病性大肠杆菌对氟喹诺酮类药物的敏感性分析 |
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| 引用本文： | 陈鲜花,李跃龙,张健騑,余永鹏,王刚,尹烨华,谭滇湘.广东鸡致病性大肠杆菌对氟喹诺酮类药物的敏感性分析[J].中国兽药杂志,2004,38(11):10-12. |
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| 作者姓名： | 陈鲜花 李跃龙 张健騑 余永鹏 王刚 尹烨华 谭滇湘 |
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| 作者单位： | 1. 广东省农科院兽医研究所,广东广州,510640
2. 广东省兽药与饲料监察所,广东广州,510230 |
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| 基金项目： | 广东省农业科技攻关项目 |
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| 摘 要： | 以广东省21个地级市为单位,从鸡场病死鸡分离细菌,选取经生化和动物试验证明的鸡致病性大肠杆菌共115株,采用药敏纸片法测定其对氟喹诺酮类药物的敏感性.结果显示,72.2 %的试验菌对氟喹诺酮类药物产生抗药性;氟喹诺酮类药物之间交叉耐药严重,恩诺沙星与氟罗沙星交叉耐药率高达99%.
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| 关 键 词： | 大肠杆菌 耐药性 药敏试验 氟喹诺酮药物 |
| 文章编号： | 1002-1280(2004)11-0010-03 |
| 修稿时间： | 2004年4月30日 |
Fluoroquinolone resistance in Escherichia coli isolated from chickens in Guangdong province |
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| CHEN Xian-hua,LI Yue-long,ZHANG Jian-fei,YU Yong-peng,WANG Gang,YIN Ye-hua,TAN Dian-xiang.Fluoroquinolone resistance in Escherichia coli isolated from chickens in Guangdong province[J].Chinese Journal of Veterinary Drug,2004,38(11):10-12. |
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| Authors: | CHEN Xian-hua LI Yue-long ZHANG Jian-fei YU Yong-peng WANG Gang YIN Ye-hua TAN Dian-xiang |
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| Institution: | CHEN Xian-hua~1,LI Yue-long~2,ZHANG Jian-fei~1,YU Yong-peng~1,WANG Gang~1,YIN Ye-hua~1,TAN Dian-xiang~1 |
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| Abstract: | Specimens were collected from sick or dead chickens from 21 cities in Guangdong province. 115 (suspected) strains were purified and then identified by biochemical test as E. coli which was lethal to chickens by animal challenging test. The experimental results of the disk diffusion test indicated that 72.2% of tested bacteria presented resistance to the fluoroquinolones including norfloxacin, ciprofloxacin, levofloxacin, ofloxacin, flero-(xacin) and enrofloxacin. There was a serious cross-resistance among the fluoroquinolone drugs. The cross-resistence rate was 99% between enrofloxacin and fleroxacin. |
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| Keywords: | Escherichia coli resistance drug sensibility test fluoroquinolones |
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