| 外泌体在哺乳动物胚胎附植中的作用研究进展 |
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| 引用本文： | 贺艳娟,刘德武,吴珍芳,洪林君,蔡更元.外泌体在哺乳动物胚胎附植中的作用研究进展[J].中国畜牧杂志,2020(2):23-28. |
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| 作者姓名： | 贺艳娟 刘德武 吴珍芳 洪林君 蔡更元 |
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| 作者单位： | ;1.华南农业大学动物科学学院国家生猪种业工程技术研究中心 |
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| 基金项目： | 2018年广东省乡村振兴战略专项“广东省畜禽地方品种保护与开发利用提升工程”;广州市科技计划项目(201904010434);国家自然科学基金项目(31802033) |
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| 摘 要： | 外泌体的分泌是不同类型的细胞间信息交流的一种重要方法,近几年发现外泌体在胚胎附植中介导胚胎与母体的信息交流起重要作用。本文综述了外泌体的主要释放机制和分离鉴定方法、子宫内膜细胞和胚胎来源的外泌体在哺乳动物中调节胚胎附植的重要作用,为提高动物胚胎附植的成功率提供新依据,也为人类体外受精、辅助生殖技术的改进提供参考资料。
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| 关 键 词： | 外泌体 胚胎附植 信息交流 蛋白 MIRNA |
Research Progress on Exosomes in Mammalian Embryo Implantation |
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| HE Yanjuan,LIU Dewu,WU Zhenfang,HONG Linjun,CAI Gengyuan.Research Progress on Exosomes in Mammalian Embryo Implantation[J].Chinese Journal of Animal Science,2020(2):23-28. |
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| Authors: | HE Yanjuan LIU Dewu WU Zhenfang HONG Linjun CAI Gengyuan |
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| Institution: | ,College of Animal Science, South China Agricultural University, National Engineering Research Center for Breeding Swine Industry |
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| Abstract: | Exosome secretion is an important method for information exchange between different types of cells. It has been found in recent years that exosomes play an important role in mediating information exchange between embryo and mother in embryo implantation. In this review, we summarized the major release mechanisms and isolation and identification methods of exosomes, and the important role of endometrial cells and embryo-derived exosomes in regulating embryo implantation in mammals, providing a new basis for improving the success rate of animal embryo implantation and a reference for the improvement of human in vitro fertilization and assisted reproductive technology. |
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| Keywords: | Exosomes Embryo implantation Information crosstalk Protein miRNA |
| 本文献已被 CNKI 维普 等数据库收录！ |
