| 盐酸克伦特罗在羊主要脏器中残留量消除规律的研究 |
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| 引用本文： | 李颖,苏晓鸥,杨静.盐酸克伦特罗在羊主要脏器中残留量消除规律的研究[J].中国畜牧兽医,2013,40(2):217-220. |
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| 作者姓名： | 李颖 苏晓鸥 杨静 |
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| 作者单位： | 中国农业科学院农业质量标准与检测技术研究所,北京 100081 |
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| 基金项目： | 公益性行业(农业)科研专项经费(20123088) |
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| 摘 要： | 本试验对盐酸克伦特罗在休药期肉羊眼睛、心脏、肾脏、肺脏、脾脏等组织中的残留规律进行了研究。选择24头体重为(30±5)kg健康肉羊进行试验,在饲料中添加50 μg/kg盐酸克伦特罗,连续饲喂35 d后休药,通过液相色谱—质谱联用/质谱检测休药期肉羊组织中克伦特罗含量,研究其残留量消除规律。试验结果表明,肉羊眼睛中有高浓度的盐酸克伦特罗残留且其在肝脏中消除较慢;停药第14天眼睛中盐酸克伦特罗的浓度仍为42.42～63.48 μg/kg,脾脏中盐酸克伦特罗消除速度是最快的;停药3 d时,检测不到盐酸克伦特罗的残留量(低于检出限0.07 μg/kg),故眼睛可用作检测盐酸克伦特罗在肉羊生产上非法使用的靶标。
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| 关 键 词： | 盐酸克伦特罗 羊 消除规律 |
| 收稿时间： | 2012-06-08 |
Study on Residues and Depletion of Clenbuterol Hdrochloride in Principal Organ of Sheep |
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| LI Ying
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SU Xiao-ou
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YANG Jing.Study on Residues and Depletion of Clenbuterol Hdrochloride in Principal Organ of Sheep[J].China Animal Husbandry & Veterinary Medicine,2013,40(2):217-220. |
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| Authors: | LI Ying SU Xiao-ou YANG Jing |
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| Institution: | Institute of Quality Standards & Testing Technology for Afro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China |
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| Abstract: | The distribution and depletion of clenbuterol hdrochloride in ovine eyes, heart, lung, kidney and spleen of sheep after treatment with dietary clenbuterol hdrochloride were studied. 24 sheep with the weight of (30±5)kg were used to determine the residues and depletion of clenbuterol hdrochloride.Sheep were fed 50 μg/kg clenbuterol hdrochloride for 35 consecutive days.Samples of ovine tissues were collected to determine clenbuterol hdrochloride concentrations by LC-MS/MS.The results showed that residues of clenbuterol hdrochloride were high in ovine eyes. The elimination of clenbuterol hdrochloride was slow in eyes. Clenbuterol hdrochloride concentration in eyes was 42.42 to 63.48 μg/kg on day 14 after withdrawal. The elimination of clenbuterol hdrochloride was the fast in spleen. Clenbuterol hdrochloride was not able to be detected (<0.7 μg/kg) in spleen on day 3 after withdrawal. So eyes could be used to monitor and confirm the illegal use of clenbuterol hdrochloride in mutton sheep. |
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| Keywords: | clenbuterol hdrochloride sheep depletio |
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