USE OF 99mTc-MERCAPTOACETYLTRIGLYCINE TO EVALUATE RENAL FUNCTION IN HORSES |
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| Authors: | Philip R Woods DVM PhD Wm Tod Drost DVM Cyril R Clarke BVSc PhD Carolyn J Rodebush RT |
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| Institution: | Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, USA. |
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| Abstract: | Ten healthy horses were injected intravenously with 99mTc-MAG3 and the disappearance of radioactivity from the blood was measured. The total body clearance (Cl(B)) and elimination half-life (t1/2(beta)) were 7.9 +/- 1.5 ml/kg/minute and 32.8 +/- 4.1 minutes, respectively. The disappearance of 99mTc-MAG3 from the blood of 2 horses with compromised renal function was also measured. The data suggest that 99mTc-MAG3 is a useful and clinically applicable radiopharmaceutical for measurement of effective renal blood flow in the horse. |
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| Keywords: | horse renal function nuclear medicine 99mTc-MAG3 |
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