Isolation of antifungal-resistant yeasts from bulk milk in Japan |
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| Authors: | Ryoka MIYAKE Takakaki ITO Hiroshi KAMATA Rui KANO |
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| Institution: | 1)Veterinary Dermatology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fusisawa, Kanagawa 252-0880, Japan;2)Veterinary Hospital Aichi P.F.A.M.A.A., 91-1 Oike, Hane-cho, Okazaki, Aichi 444-0816, Japan;3)Veterinary Pathobiology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fusisawa, Kanagawa 252-0880, Japan |
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| Abstract: | We isolated ascomycetous yeasts including Candida species, that originally belonged to the genus Candida, from bulk milk in the Aichi area of Japan, and determined the minimum inhibitory concentrations (MICs) of antifungal drugs on these isolates by conducting E-tests. We isolated 7 human pathogenic species (14 isolates) from 14 bulk milk samples: 5 Candida species of yeasts, and 2 Candida-related species. Two isolates of C. albicans and C. inconspicua were resistant to fluconazole (MIC >32 mg/l). One isolate of C. krusei was resistant to both azoles (fluconazole: >256 mg/ml and itraconazole: 4 mg/l). One isolate of C. catenulata might be resistant to amphotericin B (>32 mg/l). |
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| Keywords: | antifungal resistance bulk milk Candida cow susceptibility testing |
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