| 克隆伊氏锥虫不同VAT的某些生物学特性研究 |
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| 引用本文： | 周金林,沈杰.克隆伊氏锥虫不同VAT的某些生物学特性研究[J].中国兽医寄生虫病,1999,7(1):4-6. |
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| 作者姓名： | 周金林 沈杰 |
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| 作者单位： | 中国农科院上海家畜寄生虫病研究所 |
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| 摘 要： | 对伊氏锥虫安徽株单虫克隆ＳｈＴａｔｌ感染兔体后３、６、９和１８ｄ所分离的４个抗原变异体ＳｈＴａｔｌ．１、ＳｈＴａｔｌ．２、ＳｈＴａｔｌ．３和ＳｈＴａｔｌ．５的生长特征、对人血清敏感性和对小白鼠致病力三个方面进行了比较研究。结果表明不同抗原变异体的生物学特性不完全一致，它提示伊氏锥虫的抗原变异可能伴有虫体其它生理生化特性的改变。
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| 关 键 词： | 伊氏锥虫 单虫克隆 抗原变异体 |
STUDIES ON SOME BIOLOGICAL CHARACTERISTIC OF DIFFERENT VARIABLE ANTIGENIC TYPE FROM A CLONED TRYPANOSOMA EVANSI |
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| Zhou,Jinlin,Shen,Jie,Zhou,Yongzhi.STUDIES ON SOME BIOLOGICAL CHARACTERISTIC OF DIFFERENT VARIABLE ANTIGENIC TYPE FROM A CLONED TRYPANOSOMA EVANSI[J].Chinese Journal of Veterinary Parasitology,1999,7(1):4-6. |
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| Authors: | Zhou Jinlin Shen Jie Zhou Yongzhi |
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| Abstract: | ShTat1.l, ShTat1.2,ShTat1.3 and ShTat1.5 are four variable antigenic type (VAT)produced by a cloned trypanosoma evansi. ShTat1 which infected rabbit 3,6,9,18 days isolated trypanosomes. These VATwere taken to study their growth characteristic, sensitivity to human serum and pathogenicity to mice. ShTat1.1 Showed gathering in mice blood, while the other VATs showed dispersing in mice blood; ShTat1.1 showed more sensitive to human serum than the other VATs; the four VATs have no difference in pathogenicity to mice. The result showed biological characteristic of differnt VAT were not all the same, which implied that antigenic variation of T.evansi was accompanied with variation of trypanosome other physiology and biochemistry property. |
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| Keywords: | Variable antigenic type trypanosoma evansi biological characteristic |
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