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Failure to respond to endogenous or exogenous melatonin may cause nonphotoresponsiveness in Harlan Sprague Dawley rats |
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| Authors: | Matthew?Rocco?Price Julie?Anita Marie?Kruse M?Eric?Galvez Annaka?M?Lorincz Mauricio?Avigdor |
| Institution: | (1) Department of Biology, College of William and Mary, Williamsburg, VA 23187, USA |
| Abstract: | BackgroundResponsiveness to changing photoperiods from summer to winter seasons is an important but variable physiological trait in most temperate-zone mammals. Variation may be due to disorders of melatonin secretion or excretion, or to differences in physiological responses to similar patterns of melatonin secretion and excretion. One potential cause of nonphotoresponsiveness is a failure to secrete or metabolize melatonin in a pattern that reflects photoperiod length. |
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