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速眠新与氯胺酮复合麻醉对犬呼吸循环的影响
引用本文:王喆,谢萍,陆承荣,王红.速眠新与氯胺酮复合麻醉对犬呼吸循环的影响[J].中国兽医学报,2009,29(12).
作者姓名:王喆  谢萍  陆承荣  王红
作者单位:1. 空军总医院,临床航空医学中心实验室,北京,100142
2. 解放军总医院,外科临床部,北京,100853
基金项目:北京市朝阳区社会发展计划基金
摘    要:为观察速眠新、速眠新与氯胺酮复合麻醉时犬呼吸循环的影响,20只成年健康犬分为速眠新组和速眠新与氯胺酮复合组,各10只.速眠新组诱导时肌肉注射速眠新0.1 mL/kg;速眠新与氯胺酮复合组采用速眠新与氯胺酮肌肉注射,速眠新与氯胺酮配比度为1:2,给药量为0.2 mL/kg.术前监测诱导前、后呼吸频率(RR)、通气量(VE)、血氧饱和度(SpO_2)、呼气末二氧化碳(P_(ET)CO_2)、心率(HR)和平均动脉压(MAP)等参数.结果表明,速眠新组诱导后1 min RR、SpO_2比诱导前显著下降(P<0.05),VE下降非常显著(P<0.01),MAP、HR均低于诱导前(P<0.05).速眠新与氯胺酮诱导前、后呼吸循环参数之间无显著变化(P>0.05).

关 键 词:速眠新  氯胺酮  复合麻醉  呼吸  循环

Effect of compound anesthesia by Sumianxin with ketamine on respiration and circulation system of dogs
WANG Zhe,XIE Ping,LU Cheng-rong,WANG Hong.Effect of compound anesthesia by Sumianxin with ketamine on respiration and circulation system of dogs[J].Chinese Journal of Veterinary Science,2009,29(12).
Authors:WANG Zhe  XIE Ping  LU Cheng-rong  WANG Hong
Abstract:To observe the effect of anesthesia by Sumianxin,or combined with ketamine on respiration and circulation system of dogs,20 healthy grown dogs were divided radamly in to two groups of 10 each.One group was indueed with intramuscular injection as 0.1 mL/kg of Sumianxin,another group with intramuscular injection as 0.2 mL/kg of mixture of Sumianxin and ketamine(1:2).The respiration rate(RR)before and after induction of these chemicals were observed respectively before surgery.Furthermore,SpO_2,P_(ET)CO_2,heart rate(HR),MAP and other data were monitored as well before surgery.The result showed that RR,SpO_2,MAP and HR decreased remarkably 1 min after treatment of Sumianxin(P<0.05).VE was also found to decrease(P<0.01).However,all observed data hade no marked change before and after induction by Sumianxin together with ketamine(P>0.05).
Keywords:Sumianxin  ketamine  compound anesthesia  respiration  circulation
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