Anatomical distribution of T- and B-lymphocytes in Marek's disease--an immunohistochemical study |
| |
| Authors: | Hoffmann-Fezer G Hoffmann R |
| |
| Institution: | 1. Institut für Hämatologie der GSF, Landwehrstr. 61, 8 München 2 Federal Republic of Germany;2. Tiergesundheitsdienst Bayern, Senator-Gerauer-Straße 25, 8011 Grub Federal Republic of Germany |
| |
| Abstract: | Neural lesions of Marek's disease, Marek's disease tumours in the ovary, liver, and kidney, as well as spleen and bursa of Fabricii of chickens bearing Marek's disease tumorous infiltrations, were examined by a new immunohistochemical technique basing upon Sternbergers unlabelled antibody enzyme method which allows the exact localization of lymphoid cells based on their surface antigens. Type C neural lesions contained T-lymphocytes almost exclusively. Type B neural lesions had relatively high proportions of T- and B-lymphocytes, and severe type A neural lesions possessed one part of heavily labelled T-lymphocytes and a number of cells stained weakly by rabbit-anti-chicken-T-cell-globulin. Tumorous infiltrations had similar characteristics as type A neural lesions. Spleen and interfollicular spaces of bursa of Fabricius were infiltrated by T-lymphocytes. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
