| 原发性开角型青光眼中医证型、证候、证素文献分析研究 |
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| 作者姓名： | 李翔 彭俊 蒋鹏飞 彭清华 |
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| 作者单位： | 湖南中医药大学, 湖南 长沙 410208;中医药防治眼耳鼻咽喉疾病湖南省重点实验室, 湖南 长沙 410208,湖南中医药大学第一附属医院, 湖南 长沙 410007;中医药防治眼耳鼻咽喉疾病湖南省重点实验室, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208;中医药防治眼耳鼻咽喉疾病湖南省重点实验室, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007;中医药防治眼耳鼻咽喉疾病湖南省重点实验室, 湖南 长沙 410208 |
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| 基金项目： | 国家自然科学基金面上资助项目（30772824，81574031）；中医药防治五官科疾病湖南省重点实验室建设项目（2017TP1018）；长沙市科技计划项目（K1501014-31，kc1704005）；中央财政支持地方高校建设项目；国家中医药管理局中医眼科学重点学科建设项目；湖南省中医五官科学重点学科建设项目；湖南省研究生科研创新项目（CX2018B497）。 |
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| 摘 要： | 目的 通过文献研究，分析原发性开角型青光眼（primary open angle glaucoma，POAG）证型分布特点及其证候、证素特点，为临床POAG的诊治提供依据。方法 检索CNKI（中国知网数据库）、VIP（维普数据库）、CBM（中国生物医学文献数据库）和Wanfang数据库（万方数据库），采用EpiData3.1软件建立POAG证候文献数据库，应用统计软件SPSS 19.0进行统计分析。结果 最终纳入文献11篇，包括644例不同证型的患者，规范后的POAG证型11种，最常见的4种证型为：肝肾亏虚证（26.55%）、肝郁化火证（23.45%）、痰湿泛目证（18.94%）、肝郁气滞证（13.20%），与POAG相关的病位证素为肝，病性证素主要与阴虚、血虚、阳亢、气滞相关。结论 本研究初步反映了POAG常见证型、证候分布特点，并对其证素特点进行了概括，为临床POAG的诊疗提供依据。
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| 关 键 词： | 原发性开角型青光眼 证型 证候 证素 肝肾亏虚证 肝郁化火证 肝 阴虚 |
| 收稿时间： | 2018/9/7 0:00:00 |
Study on Traditional Chinese Medicine Syndrome Types, Syndrome Complex and Syndrome Elements of Primary Open Angle Glaucoma |
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| Authors: | LI Xiang PENG Jun JIANG Pengfei and PENG Qinghua |
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| Institution: | Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Changsha, Hunan 410208, China,The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Changsha, Hunan 410208, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Changsha, Hunan 410208, China and Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Changsha, Hunan 410208, China |
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| Abstract: | Objective Through literature research, to explore the characteristics of the syndrome types distribution, syndrome complex and syndrome elements of primary open angle glaucoma(POAG), and to provide a basis for the diagnosis and treatment of POAG in clinic. Methods The China National Knowledge Infrastructure (CNKI), Vip Database (VIP), China Biological Medicine disc (CBM) and Wanfang Data were retrieved. The POAG syndrome complex database was established using Epidata 3.1 software, and the statistical software Statistical Product and Service Solutions 19.0 (SPSS) was used for statistical analysis. Results Finally, 11 papers were selected, including 644 patients with different syndrome types. There were 11 standardized POAG syndrome types, and the most common 4 types were:liver and kidney deficiency syndrome (26.55%), liver depression transforming into fire syndrome (23.45%), phlegm-dampness assailing eye syndrome (18.94%), liver depression and Qi stagnation syndrome (13.20%). As for disease position, the syndrome element associated with POAG was liver. As for disease nature, the syndrome elements were Yin deficiency, blood deficiency, Yang hyperactivity and Qi stagnation. Conclusion This study initially reflected the distribution characteristics of common syndrome types and syndrome complex of POAG and summarized its syndrome elements, which provided a basis for the diagnosis and treatment of POAG in clinic. |
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| Keywords: | primary open angle glaucoma syndrome types syndrome complex syndrome elements liver and kidney deficiency syndrome liver depression transforming into fire syndrome liver Yin deficiency |
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