| 袁肇凯教授治疗冠心病的用药规律探析 |
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| 作者姓名： | 杨梦 胡志希 李欣春 李琳 钟森杰 姚涛 |
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| 作者单位： | 湖南中医药大学, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208,长沙金润中医院袁肇凯名师传承工作室, 湖南 长沙 410007,湖南中医药大学, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208 |
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| 基金项目： | 国家自然科学基金资助项目（81774208）；袁肇凯名师传承工作室。 |
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| 摘 要： | 目的 探讨袁肇凯教授治疗冠心病的临床用药规律。方法 收集袁肇凯教授治疗冠心病临床案例121份，运用Excel表及统计学软件SPSS 21.0进行频数分析和聚类分析。结果 121份案例中，使用中药70种，其中高频中药26种，频次排名前10的中药为川芎、炙甘草、丹参、石菖蒲、远志、白参、三七、桂枝、茯神、麦冬。获得3个聚类方：第一类方行气活血化瘀，宣通心阳，祛痰宽胸，由血府逐瘀汤与瓜蒌薤白半夏汤加减；第二类方补益心气，养血安神，由养心汤加减；第三类方温通心阳，活血行滞，由自拟宣痹冠心丸加减。结论 袁肇凯教授治疗冠心病注重温通心阳，活血行滞，兼以养心安神，主张补通二法作为本病治疗大法。
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| 关 键 词： | 冠心病 袁肇凯 聚类分析 用药规律 |
| 收稿时间： | 2019/3/29 0:00:00 |
Exploration and Analysis on Medication Rules of Professor YUAN Zhaokai in the Treatment of Coronary Heart Disease |
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| Authors: | YANG Meng HU Zhixi LI Xinchun LI Lin ZHONG Senjie and YAO Tao |
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| Institution: | Hunan University of Chinese Medicine, Changsha, Hunan 410208, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China,YUAN Zhaokai''s Master Heritage Studio, Jinrun Hospital of TCM, Changsha, Hunan 410007, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China and Hunan University of Chinese Medicine, Changsha, Hunan 410208, China |
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| Abstract: | Objective To explore clinical medication rules of Professor YUAN Zhaokai in treating coronary heart disease. Methods A total of 121 clinical cases of coronary heart disease treated by Professor YUAN Zhaokai were collected. Frequency analysis and cluster analysis were carried out with Excel table and statistical software SPSS 21.0. Results Among the 121 cases, 70 kinds of Chinese materia medica were used, in which 26 kinds Chinese materia medica were of high frequency. The top 10 of them were Rhizoma Ligustici Chuanxiong, Radix Glycyrrhizae Praeparata, Radix Salviae Miltiorrhizae, Rhizoma Acori Tatarinowii, Radix Polygalae, Radix Ginseng, Radix Notoginseng, Ramulus Cinnamomi, Sclerotium Poriae Pararadicis and Radix Ophiopogonis. Three clustering formulas were obtained:the first was for moving Qi, activating blood, resolving stasis, diffusing and unblocking heart Yang, dispelling phlegm and loosing chest, and it was modified Xuefu Zhuyu Decoction and Gualou Xiebai Banxia Decoction; the second was for benefiting heart Qi and nourishing blood for tranquillization, and it was modified Yangxin Decoction; the third was for warming and unblocking heart Yang, activating blood and moving stagnation, and it was modified self-made Xuanbi Guanxin Pills. Conclusion Professor YUAN Zhaokai pays attention to warming and unblocking heart Yang, activating blood and moving stagnation, as well as nourishing heart for tranquilization, and advocates tonifying and unblocking methods as the main treatment of coronary heart disease. |
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| Keywords: | coronary heart disease YUAN Zhaokai cluster analysis medication rules |
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