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库拉索芦荟凝胶冻干粉对胃粘膜保护作用的研究
引用本文:陈梦婷.库拉索芦荟凝胶冻干粉对胃粘膜保护作用的研究[J].现代农业科技,2023(18).
作者姓名:陈梦婷
作者单位:云南万绿生物股份有限公司
摘    要:通过将50只大鼠分为三个用量组、空白对照组和模型对照组,研究探讨了库拉索芦荟凝胶冻干粉对无水乙醇引起的大鼠急性胃粘膜损伤能否产生保护效果。样品低、中、高用量依次为0.167g/kg·bw、0.0333g/kg·bw、1.000g/kg·bw(分别相当于人体推荐量的5倍、10倍以及30倍),然后将其分别给受试小鼠灌胃,灌胃体积均为10mL/kg·bw,每天一次,连续灌胃30天,最后以无水乙醇为急性胃粘膜损伤剂,对大鼠进行解剖,通过比较大鼠胃粘膜损伤积分指数、胃粘膜病理组织学检查病变总积分的结果,表明库拉索芦荟凝胶冻干粉对于动物的胃粘膜损伤有着辅助保护功能。

关 键 词:大鼠  库拉索芦荟凝胶冻干粉  胃粘膜  损伤  辅助保护
收稿时间:2023/1/9 0:00:00
修稿时间:2023/1/9 0:00:00

Protective effect of Aloe Vera gel Freeze-driedpowder on gastric mucosa
Abstract:Fifty rats were divided into three dose groups, blank control group and model control group to study the protective effect of Aloe Vera gel freeze-dried powder on acute gastric mucosal injury induced by ethanol in rats. The low, medium and high doses of the samples were 0.167g/kg·bw, 0.0333g/kg·bw and 1.000g/kg·bw (5 times, 10 times and 30 times of the recommended amount of human body, respectively),The tested mice were given intragastric administration with the intragastric volume of 10mL/kg·bw, once a day. After 30 consecutive days, the rats were anatomized with anhydrous ethanol as the agent for acute gastric mucosal injury. According to the scores of gastric mucosal injury and the total scores of gastric mucosal pathological examination, the results showed that aloe vera gel freeze-dried powder had an auxiliary protective effect on the gastric mucosal injury.
Keywords:The rat  Aloe vera Gel freeze-dried powder  Gastric mucosa  Damage  Auxiliary protection
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