Use of bone morphogenetic proteins for augmentation of bone regeneration |
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| Authors: | Kirker-Head Carl A Boudrieau Randy J Kraus Karl H |
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| Institution: | Orthopaedic Research Laboratory, Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA. |
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| Abstract: | A large body of preclinical and clinical data now documents that recombinant BMPs can be used for skeletal regeneration in humans and animals. Recombinant human BMP-2 and BMP-7 have been approved for use in human patients with long-bone fractures and nonunions and in patients undergoing lumbar fusion or various maxillofacial and dental regenerative procedures. These products have also been made available for veterinary use. |
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