TOTAL BODY IRRADIATION FOR THE TREATMENT OF LYMPHOMA IN A GUINEA PIG (CAVIA PORCELLUS) |
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| Institution: | 1. National Autonomous University of Mexico, Mexico City, CDMX, Mexico;2. National Autonomous University of Mexico Mexico City, CDMX, Mexico;1. Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore, Pakistan;2. Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan;3. Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan;4. Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Pakistan;5. Department of Population Medicine and Diagnostic Sciences Cornell University College of Veterinary Medicine Ithaca, New York, USA;6. College of Animal Science and Technology, Yunnan Agriculture University, Kunming, 650201, Yunnan, China.;1. Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran;2. Ophthalmology Section, Negah Veterinary Centre, Tehran, Iran;3. Bu Ali Sina University, Hamadan, Iran;4. Department of Internal medicine, Veterinary Medicine Faculty, University of Tehran, Tehran, Iran;5. Department of Veterinary Medicine, Madingley Road, Cambridge, United Kingdom CB3 0ES.;1. University of Illinois, Department of Veterinary Clinical Medicine, Urbana, IL, USA;2. Mystic Aquarium, Mystic, CT, USA;3. Oxbow Animal Health, Murdock, NE, USA;4. Scovill Zoo, Decatur, IL, USA;5. Louisiana State University, Department of Veterinary Clinical Sciences, Baton Rouge, LA, USA. |
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| Abstract: | A 5-year-old intact male guinea pig was evaluated for a 2-week history of “red eyes.” Sniffling and lethargy had been noticed for several days as well. Physical examination findings included increased expiratory effort and bilateral chemosis. Several peripheral lymph nodes were markedly enlarged. Fine needle aspiration of the enlarged lymph nodes was consistent with lymphoma. The first total body irradiation with 1 Gray (Gy) resulted in a good response as evidenced by a decrease in lymphocytes and reduced sizes of the enlarged peripheral lymph nodes. The second total body irradiation with 1.2 Gy was performed 49 days after the first total body irradiation because of tumor progression. This resulted in a less noticeable response compared to the first response, including slight shrinkage of the affected lymph node. Thus, the patient was euthanized 4 weeks after the second total body irradiation. This is the first report that describes radiation therapy for spontaneously occurring lymphoma in a guinea pig. |
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