| 菲并吲哚里西啶生物碱及其盐衍生物 的生物活性研究 |
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| 引用本文： | 王开亮,吴萌,刘智慧,苏波,李玲,刘玉秀,黄润秋,刘育,汪清民.菲并吲哚里西啶生物碱及其盐衍生物 的生物活性研究[J].农药学学报,2010,12(4):507-510. |
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| 作者姓名： | 王开亮 吴萌 刘智慧 苏波 李玲 刘玉秀 黄润秋 刘育 汪清民 |
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| 作者单位： | 1.南开大学 元素有机化学国家重点实验室/元素有机化学研究所,天津 300071 |
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| 基金项目： | 国家重点基础研究发展计划(973计划)项目(2010CB126106);国家自然科学基金(20872072);中国博士后科学基金(20090460057)资助. |
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| 摘 要： | 分别采用菌丝生长速率法和盆栽法,测定了一系列菲并吲哚里西啶生物碱及其盐衍生物的杀菌及除草活性。结果表明:该类生物碱及其盐衍生物表现出了很好的杀菌活性,尤其是生物碱安托芬 ± )-antofine]( 2 )和脱氧娃儿藤宁碱 ± )-deoxytylophorinine]( 3 )在50 μ g/mL下,对番茄早疫Alternaria solani、花生褐斑Cercospora arachidicola、苹果轮纹Physalospora piricola 和黄瓜枯萎Cladosporium cucumerium 4种菌体的抑制率达70%~100%;但未表现出明显的除草活性。
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| 关 键 词： | 菲并吲哚里西啶生物碱 盐衍生物 杀菌活性 |
| 收稿时间： | 2010/7/23 0:00:00 |
| 修稿时间： | 2010/9/26 0:00:00 |
Bioactivity of phenanthroindolizidine alkaloids and their salt derivatives |
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| WANG Kai-liang,WU Meng,LIU Zhi-hui,SU Bo,LI Ling,LIU Yu-xiu,HUANG Run-qiu,LIU Yu and WANG Qing-min.Bioactivity of phenanthroindolizidine alkaloids and their salt derivatives[J].Chinese Journal of Pesticide Science,2010,12(4):507-510. |
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| Authors: | WANG Kai-liang WU Meng LIU Zhi-hui SU Bo LI Ling LIU Yu-xiu HUANG Run-qiu LIU Yu and WANG Qing-min |
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| Institution: | 1.State Key Laboratory of Elemento-Organic Chemistry/Institute of Elemento-organic Chemistry, Nankai University,Tianjin 300071,China |
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| Abstract: | Fungicidal and herbicidal activity of a series of phenanthroindolizidine alkaloid and its salt derivatives were determined by mycelial growth method and pot experiment. The results showed that the alkaloid and derivatives have good fungicidal activity, especially (±)-antofine ( 2 ) and (±)-deoxytylophorinine ( 3 ),which showed 70%-100% inhibition rate against Alternaria solani,Cercospora arachidicola,Physalospora piricola and Cladosporium cucumerium at 50 μ g/mL;however,the alkaloid and derivatives showed no herbicidal activity. |
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| Keywords: | phenanthroindolizidine alkaloids salt derivatives fungicidal activity |
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