Histopathological classification of systemic Mycobacterium avium complex infections in slaughtered domestic pigs |
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| Authors: | Hibiya Kenji Kasumi Yuko Sugawara Isamu Fujita Jiro |
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| Institution: | Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan. k068736@eve.u-ryukyu.ac.jp |
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| Abstract: | The aim of this study was to classify the histopathological features of pigs infected with Mycobacterium avium complex (MAC). We used slaughtered pig organs systemically infected with MAC. The results showed granulomatous lesions which were observed predominantly in the digestive organs and regional lymph nodes rather than respiratory organs. The histological picture showed a wide range of granulomatous stages from exudative to fibrotic reactions to the MAC infection. Eosinophils and giant cells were characteristically observed in the exudative reactions. The histopathological type in primary focus tended to be maintained in the respective organs. Most strains with the same genotype showed pathogenicity for guinea pigs irrespective of the type of granuloma. Although these findings suggest that different stages of a granulomatous lesion originating from the same causative agent might influence histological patterns, other possibilities such as the hereditary background of the host, or the effects of viral infections should be considered. |
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| Keywords: | Mycobacterium avium complex Classification Histopathological Granuloma IS1245 PigsMots clé s: Le Complexe Mycobaterium avium (MAC) Classification Histopathologie Granulome Sé quence d’ insertion gé nomique (IS) 1245 Porcs |
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