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梅迪-维斯纳病毒研究进展
引用本文:张念章,储岳峰,赵萍,高鹏程,贺英,逯忠新.梅迪-维斯纳病毒研究进展[J].动物医学进展,2011,32(3):104-107.
作者姓名:张念章  储岳峰  赵萍  高鹏程  贺英  逯忠新
作者单位:中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室农业部草食动物疫病重点开放实验室农业部畜禽病毒学重点开放实验室,甘肃兰州,730046
基金项目:国家科技基础性工作专项计划,家畜疫病病原生物学国家重点实验室基金项目,广东省兽医公共卫生公共实验室开放基金项目
摘    要:梅迪-维斯纳病毒又称绵羊进行性肺炎病毒,是绵羊进行性肺炎的病原,属于逆转录病毒科、慢病毒属.其致病过程与人类免疫缺陷病毒(HIV)相似,因此可以作为HIV感染的动物的研究模型.论文综述了梅迪一维斯纳病毒的病原学,阐述了致病机理、免疫逃避机理及引起宿主的免疫反应,并对未来的防控研究工作进行展望.

关 键 词:梅迪-维斯纳病毒  病原学  致病机理  免疫学

Progress on Maedi-Visna Virus
ZHANG Nian-zhang,CHU Yue-feng,ZHAO Ping,GAO Peng-cheng,HE Ying,LU Zhong-xin.Progress on Maedi-Visna Virus[J].Progress In Veterinary Medicine,2011,32(3):104-107.
Authors:ZHANG Nian-zhang  CHU Yue-feng  ZHAO Ping  GAO Peng-cheng  HE Ying  LU Zhong-xin
Institution:ZHANG Nian-zhang,CHU Yue-feng,ZHAO Ping,GAO Peng-cheng,HE Ying,LU Zhong-xin(Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou,Gansu,730046,China)
Abstract:Maedi-Visna virus,also known as ovine progressive pneumonia virus,which belongs to the lentivirus of the retroviridae family,is the agent of ovine progressive pneumonia.The pathogenesis of Maedi-Visna virus is similar to human immunodeficiency virus(HIV),therefore can be used as animal research models.In this paper,the etiology,pathogenesis,mechanism of immune escape and host immune response were reviewed,meanwhile gave some advisement for controlling the disease.
Keywords:Maedi-Visna virus  etiology  pathogenesis  immunology  
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