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口蹄疫病毒蛋白与细胞凋亡
引用本文:王猛,张杰,刘永生.口蹄疫病毒蛋白与细胞凋亡[J].中国农学通报,2010,26(22):7-11.
作者姓名:王猛  张杰  刘永生
作者单位:中国农业科学院兰州兽医研究所,家畜疫病病原生物学国家重点试验室,农业部畜禽病毒学重点开放试验室,农业部兽医公共卫生重点开放试验室,兰州,730046
摘    要:口蹄疫病毒(foot-and-mouth disease virus,FMDV)在感染细胞的过程中能够根据自己的需要诱导或者阻碍宿主细胞的凋亡,为自己创造最佳的生存环境并在一定程度上逃避宿主细胞的攻击,获得最大的生存能力。笔者总结了近年来对FMDV各蛋白与细胞凋亡间的研究,分析FMDV各蛋白在调节细胞凋亡过程中发挥的作用,并对FMDV的持续性感染机制的形成进行初步探讨。

关 键 词:荒漠化    荒漠化    聊城市    气候因子
收稿时间:2010/3/29 0:00:00
修稿时间:7/9/2010 12:00:00 AM

Foot and Mouth Disease Virus Proteins and Apoptosis
Yong-sheng Liu.Foot and Mouth Disease Virus Proteins and Apoptosis[J].Chinese Agricultural Science Bulletin,2010,26(22):7-11.
Authors:Yong-sheng Liu
Institution:(Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730046)
Abstract:Foot and mouth disease virus(FMDV) can induce or prevent the apoptosis of the host cell according to oneself needs in the process of infecting cells,so as to create the best living environment and to escape the attack from the host cells in a certain extent to obtain the maximize viability.This paper reviewed the different roles of the FMDV proteins in regulating host cell apoptosis homeostasis,and discussed the mechanism of FMDV persistence infection.
Keywords:eIF4G  PKR
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