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| 牛Myostatin基因单核苷酸多态性分析 | |
| 引用本文： | 史明艳,昝林森,李保兰,刘 霞,张自富.牛Myostatin基因单核苷酸多态性分析[J].中国农学通报,2005,21(6):24-24. |
| 作者姓名： | 史明艳 昝林森 李保兰 刘 霞 张自富 |
| 作者单位： | 1. 西北农林科技大学动物科技学院,陕西,杨凌,712100 2. 安阳钢铁集团公司,河南,安阳,455004 3. 延安大学生命科学学院,陕西,延安,716000 |
| 基金项目： | 农业科技跨越计划(2003-20)、国家农业科技成果转化项目(02EFN216100231)及陕西省科技攻关计划项目(2003K01-G7). |
| 摘 要： | Myostatin基因即肌肉生长抑制素，是一种肌肉生长的负调控因子。应运PCR-SSCP和测序的方法对中国秦川牛、南阳牛以及国外引入品种皮埃蒙特牛双肌基因的第三外显子进行了多态性分析。结果表明：第三外显子938处G→A的单核苷酸的突变造成了南阳牛、皮埃蒙特牛第三外显子扩增片段多态性,秦川牛则不然。 |
| 关 键 词： | 牛 Myostatin gene 单链构象多态性 |
Single Nucleotide Polymorphism Analysis of the Cattle Myostatin Gene |
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| Shi Mingyan,Zan Linsen,Li Baolan,Liu Xi,Zhang zifu.Single Nucleotide Polymorphism Analysis of the Cattle Myostatin Gene[J].Chinese Agricultural Science Bulletin,2005,21(6):24-24. | |
| Authors: | Shi Mingyan Zan Linsen Li Baolan Liu Xi Zhang zifu |
| Institution: | (1College of Animal Science and Veterinary Medicine,Northwest Science and Technology University of Agriculture and Forestry,Yang Ling Shaan Xi 712100; 2Angang group, Anyang Henan 455004； 3College of Life Sciences, Yan’an University, Yan’an Shaanxi 716 |
| Abstract: | Myostatin is a negative regulator of skeletal muscle growth. Using a pair of special primers to amplify the exon 3 of Myostatin gene in Qinchuan, Nanyang Beef and Piedmontese, we aimed to detect the polymorphisms of Myostatin gene. We found that it was G mutated to T at 938 point in exon 3 that made the polymorphisms of Myostatin gene in Nanyang Beef and Piedmontese. |
| Keywords: | Cattle Myostatin gene Single strand conformationl polymorphism |
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