| 高钾血症模型的建立及抢救措施机理的分析 |
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| 引用本文： | 姚远,张秀梅,范春玲.高钾血症模型的建立及抢救措施机理的分析[J].黑龙江八一农垦大学学报,2012,24(1):39-43,47. |
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| 作者姓名： | 姚远 张秀梅 范春玲 |
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| 作者单位： | 1. 黑龙江八一农垦大学动物科技学院,大庆,163319
2. 杜尔伯特蒙古族自治县畜牧兽医水产局 |
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| 基金项目： | 黑龙江省八一农垦大学教学研究课题 |
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| 摘 要： | 高钾血症是临床上多种疾病所并发的一种常见病理生理过程。血钾升高的最大危害是心肌毒性,它可引起机体心律失常甚至心脏停搏危及生命。因此,预防高钾血症的发生和采取有效的处理方法,一直是病理生理学研究的热点问题之一。了解高血钾对心肌细胞的毒性作用及寻找抢救方法。制备高血钾家兔模型,并分别用葡萄糖酸钙、NaHCO3进行抢救。高钾血症时,心电图可见家兔心律失常,并且T波高耸,Q—T间期缩短,同时,还会使机体的呼吸系统发生变化;用葡萄糖酸钙、NaHCO3后,抢救成功。高血钾对心脏有毒性作用,浓度升高速度越快,毒性作用越大。静脉推注高葡萄糖溶液、NaHCO3溶液都对缓解高血钾症有一定的作用;心电图可作为诊断高血钾,判定其程度和观察疗效的重要指标。
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| 关 键 词： | 高血钾 NaHCO3 葡萄糖酸钙 |
Establishment of Hyperkalemia and Analysis on the First-aid Measures |
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| Yao Yuan,Zhang Xiumei,Fan Chunling.Establishment of Hyperkalemia and Analysis on the First-aid Measures[J].Journal of Heilongjiang August First Land Reclamation University,2012,24(1):39-43,47. |
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| Authors: | Yao Yuan Zhang Xiumei Fan Chunling |
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| Institution: | 1(1.College of Animal Science and Technology,Heilongjiang Bayi Agricultural University,Daqing 163319; 2.Duerbote county animal husbandry Bureau) |
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| Abstract: | Hyperkalemia is a kind of common pathological process in many diseases.The biggest harm of hyperkalemia is its effect to cardiac muscle,which can cause cardiac arrhythmia and even death.So,it is one of the hot issues about the prevention of hyperkalemia and measures to cure it.To observe the effects of hyperkalemia in rabbits and do some measures to save the dying rabbits. A model of hyperkalemia was established and then the rabbits were saved by glucose calcium and NaHCO3 individually.Results: The electrocardiogram of the rabbits of hyperkalemia showed their arrhythmia,top and sharp of T wave and short of Q-T interval;After using NaHCO3 or glucose calcium,the rabbits could recover.Meanwhile,great changes also took place in the respiratory system. With the increasing of the potassium concentration,the toxicity to heart was growing more serious,and NaHCO3 and Glucose Calcium had positive effects on hyperkalemia. |
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| Keywords: | Hyperkalemia NaHCO3 Glucose Calcium |
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