| 中链脂肪酸及其酯对致病菌的抑菌作用 |
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| 引用本文： | 汤佳宁,王永侠,刘金松,曾新福,杨彩梅.中链脂肪酸及其酯对致病菌的抑菌作用[J].浙江农业学报,2021,33(9):1611. |
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| 作者姓名： | 汤佳宁 王永侠 刘金松 曾新福 杨彩梅 |
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| 作者单位： | 1.浙江农林大学 动物科技学院,浙江 杭州 3113002.浙江惠嘉生物科技股份有限公司,浙江 安吉 311107 |
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| 基金项目： | 浙江省重点研发计划(2019C02051);国家重点研发计划政府间国际创新合作项目(2018YFE0112700);浙江省自然科学基金(LY17C170004) |
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| 摘 要： | 中链脂肪酸甘油酯已经成为抗生素替代物研究的新热点。文章旨在探究月桂酸、单辛酸甘油酯、单月桂酸甘油酯、辛葵酸甘油酯对大肠埃希菌、金黄色葡萄球菌、肠炎沙门氏菌和鸡白痢沙门氏菌的抑菌效果。结果显示:月桂酸、单月桂酸甘油酯、单辛酸甘油酯对大肠埃希菌有显著(P<0.05)抑制作用;月桂酸、单月桂酸甘油酯、单辛酸甘油酯、辛葵酸甘油酯对金黄色葡萄球菌有显著(P<0.05)抑制作用;月桂酸、单月桂酸甘油酯、单辛酸甘油酯、辛葵酸甘油酯对肠炎沙门氏菌有显著(P<0.05)抑制作用;月桂酸、单月桂酸甘油酯、单辛酸甘油酯对鸡白痢沙门氏菌有显著(P<0.05)抑制作用。其中,月桂酸、单月桂酸甘油酯、单辛酸甘油酯对4种致病菌的作用效果随时间延长而增强。
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| 关 键 词： | 中链脂肪酸脂 大肠埃希菌 肠炎沙门氏菌 金黄色葡萄球菌 鸡白痢沙门氏菌 抑菌效果 |
| 收稿时间： | 2020-08-14 |
Bacteriostatic effect of medium-chain fatty acids and their esters on pathogenic bacteria |
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| TANG Jianing,WANG Yongxia,LIU Jinsong,ZENG Xinfu,YANG Caimei.Bacteriostatic effect of medium-chain fatty acids and their esters on pathogenic bacteria[J].Acta Agriculturae Zhejiangensis,2021,33(9):1611. |
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| Authors: | TANG Jianing WANG Yongxia LIU Jinsong ZENG Xinfu YANG Caimei |
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| Institution: | 1. College of Animal Science And Technology, Zhejiang A & F University, Hangzhou 311300, China
2. Zhejiang Huijia Bio-Technology Co., Ltd., Anji 311107, China |
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| Abstract: | Medium-chain fatty acid glycerides have become a new hot spot in the research of antibiotic substitutes. The purpose of this study was to investigate the bacteriostatic effects of lauric acid, glycerol monooctanoate, glycerol monolaurate and glycerol octanoate on Escherichia coli, Staphylococcus aureus, Salmonella enteritidis and Salmonella pullorum. The results showed that four medium-chain fatty acid glycerides had certain inhibitory effects on four kinds of pathogenic bacteria. Among them, the effects of lauric acid, glycerol monolaurate and glycerol monooctanoate on four kinds of pathogenic bacteria increased with time. |
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| Keywords: | medium chain fatty acids Escherichia coli Salmonella enteritidis Staphylococcus aureus Salmonella pullorum bacteriostatic effect |
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