| 补喂胍基乙酸对运动训练伊犁马血浆胍基乙酸、肌酸浓度的影响 |
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| 引用本文： | 刘律,李晓斌,马艳,杨昊,张文杰,鲁豪,卫鑫岚,高俊杰,欧阳文,杨开伦.补喂胍基乙酸对运动训练伊犁马血浆胍基乙酸、肌酸浓度的影响[J].新疆农业科学,2022,59(9):2267-2275. |
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| 作者姓名： | 刘律 李晓斌 马艳 杨昊 张文杰 鲁豪 卫鑫岚 高俊杰 欧阳文 杨开伦 |
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| 作者单位： | 1.新疆农业大学动物科学学院/新疆肉乳用草食动物营养重点实验室，乌鲁木齐 8300522.新疆伊犁哈萨克自治州昭苏县种马场，新疆伊犁 835699 |
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| 基金项目： | 自治区“十三五”重大专项(2017A01002-2-01) |
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| 摘 要： | 【目的】 研究补喂胍基乙酸（GAA）对伊犁马血浆胍基乙酸、肌酸浓度的影响。【方法】 选取20匹年龄为2~3岁、体重（373.2±30.53）kg]相近且经过严格训练的速度赛用伊犁马，随机分为4组，每组5匹（3♀+2♂），每日等强度训练。每匹马每天饲喂精料补充料4 kg，自由采食青干草，各组每天每匹马分别补喂0（CON组）、25（25 GAA组）、50（50 GAA组）和75 mg/kg BW（75 GAA组）的胍基乙酸。【结果】 （1）补喂胍基乙酸极显著提高了50 GAA组马匹第1~10 d以及75 GAA 组马匹7 d、10 d的饲喂后2 h血浆Cr/GAA（P<0.01），显著提高了50 GAA组马匹第7 d、10 d的饲喂后2 h血浆肌酐浓度（P<0.05）。（2）补喂胍基乙酸极显著提高了各试验组血浆Cr/GAA（P<0.01），极显著提高了50、75 GAA组马匹血浆肌酸浓度及24 h尿液肌酸代谢物排出量（P<0.01）。【结论】 补喂胍基乙酸提高了伊犁马血浆肌酸代谢物浓度，促进了伊犁马机体对胍基乙酸的快速吸收，以供机体利用，适宜添加水平为50 mg/kg BW。
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| 关 键 词： | 伊犁马 训练 胍基乙酸 肌酸 代谢 |
| 收稿时间： | 2021-11-15 |
CEffects of Supplemented with Guanidinoacetic Acid on the Plasma Guanidinoacetic Acid and Creatine Concentrations of Yili Horses During Exercise Training |
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| LIU Lv,LI Xiaobin,MA Yan,YANG Hao,ZHANG Wenjie,LU Hao,WEI Xinlan,GAO Junjie,OUYANG Wen,YANG Kailun.CEffects of Supplemented with Guanidinoacetic Acid on the Plasma Guanidinoacetic Acid and Creatine Concentrations of Yili Horses During Exercise Training[J].Xinjiang Agricultural Sciences,2022,59(9):2267-2275. |
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| Authors: | LIU Lv LI Xiaobin MA Yan YANG Hao ZHANG Wenjie LU Hao WEI Xinlan GAO Junjie OUYANG Wen YANG Kailun |
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| Institution: | 1. Xinjiang Key Laboratory of Meat & Milk Production Herbivore Nutrition， College of Animal Science，Xinjiang Agricultural University， Urumqi 830052， China2. Yili Kazak Autonomous Prefecture of Zhaosu Racecourse， Yili Xinjiang 835699， China |
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| Abstract: | 【Objective】 The purpose of this experiment was to investigate the effect of guanidine acetic acid （GAA） supplementation on the concentration of guanidinacetic acid and creatine in plasma of Yili horse. 【Method】 Twenty Yili horses aged 2 to 3 years old， similar in weight （373.2±30.53） kg， and rigorously trained for speed races， were randomly divided into 4 groups and with 5 horses （3♀+2♂） in each group， and the training intensity were consistent. Each horse was fed 4 kg of concentrate supplements per day， and freely collected dry herbage. On this basis， each horse in each group was fed with 0 （CON group）， 25 （25 GAA group）， 50 （50 GAA group） and 75 mg/kg BW （75 GAA group） guanidine acetic acid respectively. 【Result】 The results showed as follows：（1） Supplementation of guanidine acetic acid significantly increased the plasma Cr/GAA， of horses in 50 GAA group from 1 to 10 days and 75 GAA group for 7 days and 10 days at 2 hours after feeding （P<0.01） ， and significantly increased the plasma creatinine concentration at 2 hours after feeding for 7 days and 10 days in 50 GAA group （P<0.05）. （2） Supplementation of guanidine acetic acid significantly increased plasma Cr/GAA in all experimental groups （P<0.01）， and plasma creatine concentration and 24 h urine creatine metabolite excretion in 50 and 75 GAA groups were significantly increased （P<0.01）. 【Conclusion】 It can be concluded that under the conditions of this experiment， guanidine acetic acid supplementation increased the concentration of plasma creatine metabolites and promoted the rapid absorption of guanidine acetic acid in Yili horse， and the suitable level of guanidine acetic acid supplementation was 50 mg/kg BW. |
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| Keywords: | Yili horses training guanidinoacetic acid creatine metabolism |
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