| 免疫激活与抗菌药物调节研究进展 |
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| 引用本文： | 丁明星,王玉莲,朱惠玲,刘振利,袁宗辉.免疫激活与抗菌药物调节研究进展[J].华中农业大学学报,2007,26(5):741-746. |
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| 作者姓名： | 丁明星 王玉莲 朱惠玲 刘振利 袁宗辉 |
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| 作者单位： | 华中农业大学国家兽药残留基准实验室/农业部食品安全评价重点开放实验室,武汉,430070 |
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| 基金项目： | 国家自然科学基金项目(39870596)，教育部骨干教师培养计划资助项目(2000年)资助 |
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| 摘 要： | 免疫激活主要通过多种细胞因子影响动物食欲和促进机体蛋白质及糖类分解,降低动物的生长性能。抗菌药物可调节免疫细胞活性,影响机体免疫激活状态。现有的研究提示,在应用抗菌药时除应注意考虑其在体内的药效外,还应考虑其免疫调节作用,以维护动物健康,促进动物生长。
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| 关 键 词： | 免疫激活 抗菌药 免疫调节 |
| 文章编号： | 1000-2421（2007）05-0741-06 |
| 修稿时间： | 2007-01-28 |
Development of Immune Activation and Its Modification of Antibiotics |
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| DING Ming-xing,WANG Yu-lian,ZHU Hui-ling,LIU Zhen-li,YUAN Zong-hui.Development of Immune Activation and Its Modification of Antibiotics[J].Journal of Huazhong Agricultural University,2007,26(5):741-746. |
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| Authors: | DING Ming-xing WANG Yu-lian ZHU Hui-ling LIU Zhen-li YUAN Zong-hui |
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| Institution: | National Reference Laboratory of Veterinary Drug Residues /MOA Key Laboratory of Food Safety Evaluation, Huazhong Agricultural University ,Wuhan 430070, China |
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| Abstract: | Immune activation reduces animal growth performance by multiple cytokines'suppressing animal's appetite and catabolizing proteins and saccharides.Antibiotics can modify immune activation by its effect on activities of immune cells.Studies suggest that in vivo effectiveness of antibiotics and their immune regulations both must be considered to maintain animal's health and to promote growth when they are applied. |
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| Keywords: | immune activation antibiotics immunomodification |
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