| Extraction of betulin from bark of Betula platyphylla by supercritical carbon dioxide extraction |
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| 作者姓名： | ZHANGYu-hong YUTao WANGYang |
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| 作者单位： | NortheastForestryUniversity,Harbin150040,P.R.China |
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| 摘 要： | Betulin, which is a medicinal pentacyclic triterpene, is abundant in the bark of white birch (Betula platyphlly). The bark of birch was collected at Tayuan Forest Farm of Jiagedaqi, Heilongjiang Province in September 2000. Supercritical fluid extraction (SFE) that is a new separation technology has been used for the processing pharmaceutical and natural products. In this paper, the extraction of betulin from the bark of birch by supercritical CO2 extraction was studied. The authors investigated and analyzed a few parameters such as modifier dosage, extraction pressure and extraction temperature. The optimal extraction conditions showed that the modifier dosage used for per gram bark powder was 1.5 mL, the extraction pressure was at 20 Mpa, and the extraction temperature was at 55 ℃. The velocity of flow of liquid CO2 was at 10 kg/h. The pressure and temperature in separation vessel were at 5.5 Mpa and 50 ℃, respectively.
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| 关 键 词： | 白桦 桦木醇 超临界二氧化碳萃取 提取工艺 萃取条件 药用成分 |
| 收稿时间： | 5 March 2003 |
Extraction of betulin from bark of<Emphasis Type="Italic">Betula platyphylla</Emphasis> by supercritical carbon dioxide extraction |
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| ZHANGYu-hong YUTao WANGYang.Extraction of betulin from bark of Betula platyphylla by supercritical carbon dioxide extraction[J].Journal of Forestry Research,2003,14(3):202-204. |
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| Authors: | Zhang Yu-hong Yu Tao Wang Yang |
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| Institution: | (1) Northeast Forestry University, 150040 Harbin, P.R. China |
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| Abstract: | Betulin, which is a medicinal pentacyclic triterpene, is abundant in the bark of white birch (Betula platyphlly). The bark of birch was collected at Tayuan Forest Farm of Jiagedaqi, Heilongjian Province in September 2000. Supercritical
fluid extraction (SFE) that is a new separation technology has been used for the processing pharmaceutical and natural products.
In this paper, the extraction of betulin from the bark of birch by supercritical CO2 extraction was studied. The authors investigated and analyzed a few parameters such as modifier dosage, extraction pressure
and extraction temperature. The optimal extraction conditions showed that the modifier dosage used for per gram bark powder
was 1.5 mL, the extraction pressure was at 20 Mpa, and the extraction temperature was at 55 °C. The velocity of flow of liquid
CO2 was at 10 kg/h. The pressure and temperature in separation vessel were at 5.5 Mpa and 50 °C, respectively.
Foundation item: This paper was supported by Natural Science Foundation of Heilongjiang.
Biography: ZHANG Yu-hong (1972-), male, Lecturer in Northeast Forestry University, Harbin 150040, P. R. China
Responsible editor: Zhu Hong |
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| Keywords: | Betula platyphlly Betulin Supercritical CO2 extraction |
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