The efficacy of a single intraperitoneal injection of either flumequine or oxytetracycline hydrochloride in prevention of outbreaks of atypical Aeromonas
salmonicida infection in goldsinny wrasse, Ctenolabrus
rupestris L., following stress. |
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| Authors: | Ole Bent Samuelsen Arne Ervik Lise Torkildsen Øivind Bergh |
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| Institution: | (1) Department of Aquaculture, Institute of Marine Research, N-5817 Bergen, Norway |
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| Abstract: | In this investigation, the efficacy of a single intraperitonealinjection of either flumequine or oxytetracycline hydrochloride to preventoutbreak of atypical Aeromonas salmonicida infection ingoldsinny wrasse, Ctenolabrus rupestris, following stresswas studied. Six groups of goldsinny wrasse, each of 50 individuals, weretreated with an intraperitoneal injection of either propylene glycol : saline(50 : 50), 200 mg kg–1 of oxytetracycline or 50mg kg–1 of flumequine dissolved in propyleneglycol : saline (50 : 50). Three days following medication the fish in allgroups were stressed by an intraperitoneal injection of prednisolone acetate(0.05 ml) and a rise in seawater temperature from 9 to 11°C. Mortality was observed daily for 21 days. Flumequine wasthe more effective with a mean cumulative mortality of 5% compared tooxytetracycline with 54%. The mean cumulative mortality in the unmedicatedcontrol groups was 84%. Bacterial examination of kidneys from dead fishconfirmed the presence of atypical A. salmonicida as theprobable cause of death. Minimum inhibitory concentration (MIC) values forflumequine and oxytetracycline against the isolated A.salmonicida were determined to 0.13  gml–1, and 2.0 g ml–1,respectively. |
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| Keywords: | Diseases Drugs Efficacy Goldsinny wrasse |
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