Decreased transport of orally administered protein into the blood circulation of developing juveniles of Japanese eel Anguilla japonica |
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| Authors: | Osamu Nakamura Yuzuru Suzuki Katsumi Aida Hajime Hatta |
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| Institution: | School of Fisheries Sciences, Kitasato University, Sanriku, Iwate 022-0101;, Fisheries Laboratory, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Maisaka, Shizuoka 431-0211;, Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113-0032 and; Department of Food and Nutrition, Kyoto Women's University, Higashiyama, Kyoto 605-8501, Japan |
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| Abstract: | ABSTRACT: To clarify the quantitative changes in the transport of orally intubated protein into the blood circulation as macromolecules in development, immunoglobulin Y (IgY) extracted from chicken eggs was administered orally to juvenile Japanese eel, Anguilla japonica . For the first experiment, which was performed before the commencement of artificial feeding, the oral delivery of 2.0 μg/0.1 g bodyweight of IgY resulted in a rapid increase in plasma IgY to a maximum of 2.30 μg/mL. However, the transport of IgY into the blood decreased significantly in the experiments that followed, which were performed after 12, 25 and 42 days. During this period, bodyweight increased approximately by a factor of eight, and rapid growth of the stomach was observed histologically. Possible contributions for the development of the alimentary canal to the diminishment of intestinal protein assimilation are discussed. |
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| Keywords: | gastrointestinal tract immunoglobulin Y Japanese eel juvenile oral administration protein absorption |
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