Nutriphysiological and cytological responses of juvenile channel catfish (Ictalurus punctatus) to dietary oxidized fish oil |
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| Authors: | GF Dong F Huang XM Zhu L Zhang MX Mei QW Hu HY Liu |
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| Institution: | 1. Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, , Wuhan, China;2. State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, , Wuhan, China;3. Yangtze River Fisheries Research Institute, Chinese Academy of Fisheries Science, , Wuhan, China |
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| Abstract: | An 86‐day growth trial was conducted to investigate the effect of dietary oxidized fish oil on the growth and cytopathology of juvenile channel catfish (Ictalurus punctatus). Four diets containing 0 g kg?1 (control: fresh fish oil), 30 g kg?1 (low‐oxidized oil group), 60 g kg?1 (medium‐oxidized oil group) and 90 g kg?1 (high‐oxidized oil group) graded oxidized oil levels with the same dietary lipid level (90 g kg?1 diet) were evaluated. The results show that the specific growth rate decreased with increasing dietary oxidized oil level (P < 0.05). All examined liver and kidney tissues in all dose groups exhibited what appeared as dose‐dependent cellular modifications. In addition, lipid droplet accumulation in the hepatocytes of fish in all dose groups was increased, and their localizations were distinctly different between all dose groups. The ultrastructural changes suggest the progression of mitochondrial vacuolation, especially in the renal tubules, in all dose groups. These results reveal a previously underappreciated effect of dietary oxidized fish oil on channel catfish kidneys. Overall, a series of nutriphysiological responses were adversely affected by exposure to dietary oxidized fish oil, and the corresponding interference patterns on the metabolism and transport of nutrients within cells were observed. |
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| Keywords: | cytological response
Ictalurus punctatus
lipid droplets nutriphysiological response oxidized fish oil |
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