| 石香薷挥发油体外抗病毒作用研究 |
| |
| 引用本文： | 葛冰,卢向阳,蒋红梅,方俊,莫瑾,谢馥交.石香薷挥发油体外抗病毒作用研究[J].中兽医医药杂志,2005,24(2):3-5. |
| |
| 作者姓名： | 葛冰 卢向阳 蒋红梅 方俊 莫瑾 谢馥交 |
| |
| 作者单位： | 湖南农业大学生化与发酵工程实验室,湖南,长沙,410128 |
| |
| 摘 要： | 采用有机溶剂法提取了石香薷挥发油，采用体外细胞培养的方法研究石香薷挥发油对新城疫病毒(NDV)感染的拮抗作用，测定其对鸡胚成纤维细胞的最大无毒浓度(TDo)、半数细胞中毒浓度(TD50)、抑制50％细胞病变的药物浓度(IC50)、治疗指数(TI)及体外抗NDV效果。试验结果表明：石香薷挥发油的TDo、TD50、IC50、TI分别为1．56g／l、3.13g/l、0.20g/l、15．65，石香薷挥发油0．79g/l对NDV所致的CPE有明显的抑制作用，证明石香薷挥发油具有明显的抗NDV作用，提示石香薷挥发油可以作为一种新的抗NDV感染的药物。
|
| 关 键 词： | 挥发油 石香薷 抗病毒作用 鸡胚成纤维细胞 体外细胞培养 有机溶剂法 新城疫病毒 NDV 拮抗作用 药物浓度 细胞病变 试验结果 IC50 抑制作用 CPE 感染 中毒 |
| 文章编号： | 1000-6354(2005)02-0003-03 |
| 修稿时间： | 2004年10月12 |
Antiviral effect of volatile oil from Mosla Chinensis Maxim on NDV in vitro |
| |
| GE Bing,LU Xiang-yang,JIANG Hong-mei,FANG Jun,MO Jin,XIE Fu-jiao.Antiviral effect of volatile oil from Mosla Chinensis Maxim on NDV in vitro[J].Journal of Traditional Chinese Veterinary Medicine,2005,24(2):3-5. |
| |
| Authors: | GE Bing LU Xiang-yang JIANG Hong-mei FANG Jun MO Jin XIE Fu-jiao |
| |
| Abstract: | Volatile oil was extracted from Mosla Chinensis Maxim with petroleum ether, and cell culture was utilized to investigate the anti-NDV effect of volatile oil from Mosla Chinensis Maxim. Its TD_0, TD_(50), IC_(50), TI and antiviral effect in vitro to chick embryo fibrobast (CEF) were tested. The results showed that the TD_0, TD_(50), IC_(50) and TI of volatile oil of Mosla Chinensis Maxim was 1.56 g/l, 3.13 g/l, 0.20 g/l and 15.65. Its inhibition effect on CPE caused by NDV was obvious at the dose of 0.79 g/l. This proved volatile oil of Mosla Chinensis Maxim had obvious anti-NDV effect. Therefore, it is a promising drug of anti-NDV infection. |
| |
| Keywords: | volatile oil of Mosla Chinensis Maxim NDV antiviral effect in vitro |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
