| 两种壳聚糖对小鼠增重和免疫机能影响的试验研究 |
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| 引用本文： | 丁辉景,张力,蒋春茂,陈桂银.两种壳聚糖对小鼠增重和免疫机能影响的试验研究[J].中国畜牧兽医,2008,35(11):13-16. |
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| 作者姓名： | 丁辉景 张力 蒋春茂 陈桂银 |
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| 作者单位： | 1.甘肃农业大学动物科技学院，兰州 730070; 2.江苏畜牧兽医职业技术学院畜牧系，泰州 225300; 3.江苏倍康药业有限公司，泰州 225300 |
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| 摘 要： | 壳聚糖是一种天然来源的碱性多糖,安全无毒，具有广泛的生物活性作用。作者对壳聚糖促生长、增强动物免疫力的作用进行比较研究。研究结果表明，整个试验阶段各组小鼠的日采食量和日增重差异不显著（P>0.05）；1号与2号壳聚糖高剂量组的T淋巴细胞ANAE阳性率极显著(P<0.01)高于空白对照组，并显著高于其他各添加壳聚糖组（P<0.05）；两种壳聚糖的中、高剂量组的吞噬指数、溶菌酶含量与空白对照组相比均有极显著差异（P<0.01）；1号与2号壳聚糖相比，对小鼠碳廓清指数影响的差异极显著（P<0.01），而对血清溶菌酶含量差异显著（P<0.05）；壳聚糖对小鼠感染兔源大肠杆菌有保护作用，1号壳聚糖保护效果好于2号壳聚糖。
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| 关 键 词： | 壳聚糖 小鼠 增重 免疫机能 |
The Effects on Weight Gain and Immunity of Two Kinds of Chitosan on Rats |
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| DING Hui-jing,ZHANG Li,JIANG Chun-mao,CHEN Gui-yin.The Effects on Weight Gain and Immunity of Two Kinds of Chitosan on Rats[J].China Animal Husbandry & Veterinary Medicine,2008,35(11):13-16. |
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| Authors: | DING Hui-jing ZHANG Li JIANG Chun-mao CHEN Gui-yin |
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| Institution: | 1.College of Animal Science,Agricultural University of Gansu, Lanzhou 730070, China； 2.Animal Science College of Jiangsu, Taizhou 225300, China； 3.Jiangsu Beikang Pharmacy Co. Ltd.， Taizhou 225300, China |
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| Abstract: | Chitosan is a kind of crude polysaccharid with cation in the nature, it has vast biologic function .This test was conducted to evaluat the effects of weight gain rate ,immunity on mice of two kinds of chitosan.The results showed that the intake and daily gain of mice in every group was not significant（P>0.05）; The highest dosage of two kinds of chitosan extremly imprument the T lymphocyte persentage in blood of mice(P<0.01) ,they are also higher than the other groups mice of taking chitosan (P<0.05); The second,third,fifth,sixth groups’α and content of bacteriolysin were extremely higher than contrast group(P<0.01);The effect between two kinds of chitosan on K were terribely notable(P<0.01),the effect on content of bacteriolysin of the first kind of chitosan was higher than the second one(P<0.05),still;The two kinds of chitosan had defend effect on the ratio of the mice infected by coliform,but the first kind chitosan was better than the second one. |
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| Keywords: | chitosan rats weight gain immunity |
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