Iridium-192 interstitial brachytherapy as adjunctive treatment for canine cutaneous mast cell tumors |
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| Authors: | Northrup Nicole C Roberts Royce E Harrell Todd W Allen Karen L Howerth Elizabeth W Gieger Tracy L |
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| Institution: | Department of Small Animal Medicine and Surgery, Comparative Oncology Program, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA. |
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| Abstract: | Eleven dogs with cutaneous mast cell tumors (MCTs) were treated with surgery and iridium-192 ((192)Ir) interstitial brachytherapy. Minimum tumor doses ranged from 47.2 to 63.3 Gy. Treated tumors were classified as grade II (n=7) or III (n=4). Five dogs had recurrences with a median progression-free interval of 1391 days, and six dogs had no recurrence at a median follow-up time of 942 days. Acute adverse effects were well tolerated, and late effects were mild. One dog developed a second tumor of a different cell type in the radiation treatment field. |
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