| 常用抗菌药物对东北地区猪源链球菌的体外抗菌活性研究 |
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| 引用本文： | 闫清波,苑青艳,赵志惠,李晓云,郭春艳,陆佳,石发庆,李一经,李艳华.常用抗菌药物对东北地区猪源链球菌的体外抗菌活性研究[J].中国预防兽医学报,2007,29(12):977-980. |
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| 作者姓名： | 闫清波 苑青艳 赵志惠 李晓云 郭春艳 陆佳 石发庆 李一经 李艳华 |
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| 作者单位： | 东北农业大学,动物医学学院,黑龙江,哈尔滨,150030 |
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| 基金项目： | 科技部科技攻关项目;博士后研究人员落户黑龙江科研启动资金;黑龙江省教育厅科学技术研究项目;黑龙江省青年科学技术专项资金;哈尔滨市科技攻关项目 |
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| 摘 要： | 采用微量稀释法(27种药物)和琼脂扩散法(7类药物)分别对临床分离的101株猪源链球菌进行了体外耐药性研究。以美国临床检验标准委员会(CLSI/NCCLS)的临界浓度和抑菌圈直径做为判断标准,判定了其对27种药物的耐药性和7类药物的耐药谱。结果表明,临床分离的菌株以耐药菌为主,且100%的菌株呈多重耐药;对头孢菌素类(100%)、磺胺类药物(96%～100%)、大环内酯类(97%～99%)、四环素类(98%)、青霉素类(94%～97%)耐药性最为严重,氟喹诺酮类药物(48%～91%)耐药性次之,共有25种不同的耐药谱型。结果表明,在东北地区分离到的猪源链球菌以多重耐药为主。
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| 关 键 词： | 微量稀释法 琼脂扩散法 猪源链球菌 耐药性 耐药谱 |
| 文章编号： | 1008-0589（2007）12-0977-04 |
| 收稿时间： | 2007-07-15 |
| 修稿时间： | 2007年7月15日 |
Antimicrobial susceptibility in vitro of 27 drugs axgainst Streptococcus suis in the northeast regions of China |
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| YAN Qing-bo,YUAN Qing-yan,ZHAO Zhi-hui,LI Xiao-yun,GUO Chun-yan,LU jia,SHI Fa-qing,LI Yi-jing,LI Yan-hua.Antimicrobial susceptibility in vitro of 27 drugs axgainst Streptococcus suis in the northeast regions of China[J].Chinese Journal of Preventive Veterinary Medicine,2007,29(12):977-980. |
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| Authors: | YAN Qing-bo YUAN Qing-yan ZHAO Zhi-hui LI Xiao-yun GUO Chun-yan LU jia SHI Fa-qing LI Yi-jing LI Yan-hua |
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| Abstract: | Susceptibility of 101 Streptococcus suis to 27 drugs were surveyed for minimal inhibitory concentration(MIC)by microdilution test and inhibition zone diameter to 7 antibiotics were evaluated by agar diffusion test in vitro based on the clinical and laboratory standards of institute/National Committee for Clinical Laboratory Standards(CLSI/NCCLS).None of the strains were susceptible to antimicrobial compounds tested.Most isolates were resistant to cephalosporins(100%),sulfonamides(96% -100%),macrolides(97%-99%),tetmcyclines(98%),Penicillins(94%-97%)and fluoroquinolone(48%-91%).The strains showed 25 different drug resistant spectrum.Multiple drug resistance isolates were found mainly existed in the Northeast regions of China. |
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| Keywords: | microdilution test agar diffusion test Streptococcus suis drug resistance resistant patterns |
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