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ULTRASONOGRAPHY OF ALIMENTARY LYMPHOSARCOMA IN THE CAT
Authors:Dominique G  Penninck  DVM  Antony S  Moore  BVSc  MVSc  Amy S  Tidwell  DVM  Michael E  Matz  DVM  Greg O  Freden  DVM
Institution:Department of Surgery, Section of Radiology, Tufts University, School of Veterinary Medicine and Medicine, North Grafton, MA 01536.;Department of Medicine, Tufts University, School of Veterinary Medicine and Medicine, North Grafton, MA 01536.;Department of Pathology, Tufts University, School of Veterinary Medicine and Medicine, North Grafton, MA 01536.
Abstract:Clinical, radiological and ultrasonographic findings from 22 cats with gastrointestinal lymphosarcoma were reviewed. The most common clinical findings were anorexia, weight loss, vomiting, lethargy, depression, fever, anemia and a palpable abdominal mass. Abdominal radiographs of 12 cats revealed a mass associated with the gastrointestinal tract and/or mesentery, and decreased serosal detail, suggestive of peritoneal effusion. The most common ultrasonographic finding was transmural gastric or intestinal thickening associated with loss of normal wall layering, reduced wall echogenicity and localized hypomotility. As is noted in people, other patterns such as transmural-segmental, transmural-nodular, transmural-bulky and mucosal infiltration were represented. In 3 cats, mesenteric lymph-adenopathy was responsible for most of the mass-effect. Fine-needle aspiration biopsy, automated microcore biopsy, endoscopic biopsy or necropsy confirmed the diagnosis of lymphosarcoma in all cats. Chemotherapy was instituted in 19 cats. Only 6 cats had a complete response to treatment. The results of this study indicate that ultrasonography is a valuable tool for the diagnosis of feline alimentary lymphosarcoma and that biopsies can be obtained under ultrasonographic guidance.
Keywords:feline  gastrointestinal lymphosarcoma  ultrasonography  percutaneous fine-needle aspiration biopsy  percutaneous automated microcore biopsy
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